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BACKGROUND Urban slum populations in Africa continue to grow faster than national populations. Health strategies that focus on non-communicable diseases (NCD) in this segment of the population are generally lacking. We determined the prevalence of diabetes and associated cardiovascular disease (CVD) risk factors correlates in Kibera, Nairobi's largest slum.(More)
OBJECTIVE To determine the prevalence of HCV and HCV/HIV co-infection among medical in-patients at the Kenyatta National Hospital. DESIGN Prospective cross-sectional descriptive study. SETTING Kenyatta National Hospital, a tertiary referral and teaching hospital, in-patient department SUBJECTS HIV/AIDS and HIV negative in-patients at KNH medical(More)
OBJECTIVE To evaluate the utility of Total Lymphocyte Count (TLC) as a surrogate marker for CD4 + T cell count in antiretroviral (ARV) treatment initiation in a Kenyan population of HIV seropositive patients at Kenyatta National Hospital. DESIGN Cross-sectional descriptive study. SETTING Kenyatta National Hospital, HIV treatment and follow-up outpatient(More)
BACKGROUND Highly active antiretroviral therapy (HAART) has dramatically reduced AIDS morbidity and mortality, however long-term metabolic consequences including dysglycaemia and dyslipidemia have raised concern regarding accelerated cardiovascular disease risk. OBJECTIVE To determine the period prevalence of dyslipidemia and dysglycaemia in HIV-infected(More)
BACKGROUND Urbanisation has been described as a key driver of the evolving non-communicable disease (NCD) epidemic. In Africa, hypertension is the commonest cardiovascular problem. We determined the prevalence and risk factor correlates of hypertension in the largest Nairobi slum. METHODS In 2010 we conducted a population-based household survey in Kibera,(More)
BACKGROUND Coronary artery disease (CAD) is a growing epidemic on the African continent. It remains uncertain whether the risk factors identified as contributing to CAD in white populations contribute to a similar extent to CAD incidence in black populations. No data of the local population exists that is based on the coronary angiogram (CA). OBJECTIVES(More)
OBJECTIVE To determine the prevalence of acute coronary syndromes among type 2 diabetic patients presenting to Accident and Emergency department. DESIGN Prospective cross-sectional study. SETTING Kenyatta National Hospital, a tertiary teaching and referral hospital. SUBJECTS Type 2 diabetic patients with ischaemic electrocardiograms (ECG). MAIN(More)
OBJECTIVE To describe the distribution of serum high-sensitivity C-reactive protein (hsCRP) in type 2 diabetes mellitus outpatients, and relate it to cardiovascular disease risk. DESIGN Cross-sectional descriptive study. SETTING Kenyatta National Hospital, a tertiary referral hospital. SUBJECTS One hundred and ninety seven type 2 diabetic outpatients(More)
OBJECTIVE To determine platelet abnormalities in patients with menigococcal meningitis. DESIGN Case control study. SUBJECTS Fifty seven cases of mennigococcal meningitis based on a cerebrospinal fluid gram stain for gram negative diplococcus or positive culture were recruited. Fifty-seven controls matched for age and sex were also recruited. The(More)