Mark Clee

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Using 24-hour ambulatory electrocardiographic (ECG) monitoring, the incidence of cardiac dysrhythmias was investigated in 50 apparently healthy elderly subjects aged over 60 years. There was a high incidence of both ventricular and supraventricular ectopic beats, supraventricular tachycardia and sinus arrest. First- and second-degree block were also noted.(More)
Astemizole, a new oral long acting antihistamine devoid of significant central, sedative or anticholinergic effects, was studied in nine patients with exercise-induced asthma. Most patients received some protection with the active drug after 1 week of treatment (10 mg daily) and all showed less of a fall in FEV1 on exercise 1 week after stopping the drug(More)
Muscular dystrophies (MDs) consist of a genetically heterogeneous group of disorders, recessive or dominant, characterized by progressive skeletal muscle weakening. To date, no effective treatment is available. Experimental strategies pursuing muscle regeneration through the transplantation of stem cell preparations have brought hope to patients affected by(More)
In view of the importance of determination of cell type in patients with bronchial carcinoma who are to be given chemotherapy a series of 140 histologically proved cases was analysed to assess the accuracy of pretreatment diagnosis by cytology and bronchial biopsy. Final histological diagnosis was made after thoracotomy (131 cases) or necropsy (9 cases).(More)
In a retrospective study of 377 patients with bronchial carcinoma, sputum had been reported positive or suspicious for malignant cells in 59.7%. The most important factors contributing to a positive result were the histological cell type and the site of the tumour as assessed at bronchoscopy. Significantly more positive results were obtained in epidermoid(More)
In a retrospective survey of 337 patients who had a resection for bronchial carcinoma data were obtained on 14 preoperative and two operative variables. Factors significantly adversely influencing survival were weight loss, chest pain, raised erythrocyte sedimentation rate, tumour larger than 5 cm, cell type other than squamous, pneumonectomy and tumour(More)
Bronchocentric granulomatosis has no specific clinical, radiological or immunological features, the diagnosis remains that of morphology on biopsy or resected lung tissue. The morphological features of bronchocentric granulomatosis can occur in a variety of situations and we believe this pathology reflects one of the limited ways in which bronchi can(More)
Two patients with tracheobronchopathia osteochondroplastica are described, both presenting with features suggestive of bronchial carcinoma. They had a long standing history of recurrent haemoptysis. The characteristic bronchoscopic, radiological and histological features of the condition are illustrated and the clinical problems in diagnosis discussed.
Anaphylaxis presents in children with rapid involvement of typically 2 or more organ systems including cutaneous, gastrointestinal, and respiratory. Caustic ingestions (CI) may also present with acute involvement of cutaneous, gastrointestinal, and respiratory systems. We present 2 cases of "missed diagnosis" that illustrate how CI presenting with(More)