Mark Chih-Wei Hsu

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BACKGROUND It has been suggested that gut microbiota is altered in Type 2 Diabetes Mellitus (T2DM) patients. OBJECTIVE This study was to evaluate the effect of the prebiotic xylooligosaccharide (XOS) on the gut microbiota in both healthy and prediabetic (Pre-DM) subjects, as well as impaired glucose tolerance (IGT) in Pre-DM. SUBJECTS/METHODS Pre-DM (n(More)
PURPOSE OF REVIEW To review optical imaging technologies in urologic surgery aimed to facilitate intraoperative imaging and tissue interrogation. RECENT FINDINGS Emerging new optical imaging technologies can be integrated in the operating room environment during minimally invasive and open surgery. These technologies include macroscopic fluorescence(More)
Heme oxygenase-1 (HO-1), the rate-limiting enzyme in heme degradation, is a cytoprotective enzyme upregulated in the vasculature by increased flow and inflammatory stimuli. Human genetic data suggest that a diminished HO-1 expression may predispose one to abdominal aortic aneurysm (AAA) development. In addition, heme is known to strongly induce HO-1(More)
A novel microbubble contrast agent is developed for deep tissue imaging of cancer lesions. Ultrasound-induced fluorescence modulation of the microbubbles can enable high contrast, tumor sensitive optical imaging with ultrasound-scale sub-millimeter spatial resolution. Fluorescence intensity modulation was detected in a custom acousto-fluorescence setup.(More)
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