Mark C. Evans

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Recent efforts in HIV-1 vaccine design have focused on immunogens that evoke potent neutralizing antibody responses to a broad spectrum of viruses circulating worldwide. However, the development of effective vaccines will depend on the identification and characterization of the neutralizing antibodies and their epitopes. We developed bioinformatics methods(More)
Accurate co-receptor tropism (CRT) determination is critical for making treatment decisions in HIV management. We created a genotypic tropism prediction tool by utilizing the case-based reasoning (CBR) technique that attempts to solve new problems through applying the solution from similar past problems. V3 loop sequences from 732 clinical samples with(More)
  • M M J L Turell, D J O 'guinn, J W Dohm, Jones, D J Dohm, M R Sardelis +47 others
  • 2004
the pervasiveness of hybrids between Cx. pipiens and Cx. molestus in North America, but not in Europe and Af-rica, still remains to be determined. In southernmost Europe, we identified two populations with a few hybrid individuals, as well as populations with pure Cx. pipiens signatures and populations with a mix of pure Cx. pipiens and pure Cx. molestus(More)
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