Mark Browne

Learn More
A customized laser combiner was designed and constructed for dual channel single molecule imaging. The feasibility of a combiner-incorporated imaging system was demonstrated in studies of single molecule FRET. Distance rulers made of dual-labeled dsDNA were used to evaluate the system by determining the distance between one FRET pair. The results showed(More)
An automated unsupervised technique, based upon a Bayesian framework, for the segmentation of low light level imagery is proposed. Primarily, Mixture Modelling is used to provide a baseline estimate. This estimate is then refined to consider spatial correlations using Markov Random Field (MRF) Modelling. The technique has been implemented assuming low-light(More)
  • 1