Mark Barber

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On the basis that ozone (O3) can upregulate cellular antioxidant enzymes, a morphological, biochemical and functional renal study was performed in rats undergoing a prolonged treatment with O3 before renal ischaemia. Rats were divided into four groups: (1) control, a medial abdominal incision was performed to expose the kidneys; (2) ischaemia, in animals(More)
Seventeen subjects performed resistance training of the leg extensor and flexor muscle groups two (2/wk) or three (3/wk) times per week. Changes in the relative myosin heavy chain (MHC) isoform contents (I, IIa and IIx) of the vastus lateralis and isometric, isokinetic and squat-lift one-repetition maximum (1 RM) strength were compared between conditions(More)
We aimed to quantify the association of blood interleukin-6 (IL-6) concentrations with poor outcome after stroke and its added predictive value over clinical information. Meta-analysis of 24 studies confirmed this association with a weighted mean difference of 3.443 (1.592-5.294) pg/mL, despite high heterogeneity and publication bias. Individual participant(More)
BACKGROUND Increasing evidence suggests that use of augmented visual feedback could be a useful approach to stroke rehabilitation. In current clinical practice, visual feedback of movement performance is often limited to the use of mirrors or video. However, neither approach is optimal since cognitive and self-image issues can distract or distress patients(More)
BACKGROUND Timely provision of an ankle-foot orthosis (AFO) orthotist customized for individuals early after stroke can be problematic. OBJECTIVE To evaluate the efficacy of a therapist-made AFO (SWIFT Cast) for walking recovery. METHODS This was a randomized controlled, observer-blind trial. Participants (n = 105) were recruited 3 to 42 days(More)
BACKGROUND In Scotland all non-obstetric, non-psychiatric acute inpatient and day case stays are recorded by an administrative hospital discharge database, the Scottish Morbidity Record (SMR01). The Scottish Stroke Care Audit (SSCA) collects data from all hospitals managing acute stroke in Scotland to support and improve quality of stroke care. The aim was(More)
BACKGROUND The presence of a 'weekend' effect has been shown across a range of medical conditions, but has not been consistently observed for patients with stroke. AIMS We investigated the impact of admission time on a range of process and outcome measures after stroke. METHODS Using routine data from National Scottish data sets (2005-2013), time of(More)
BACKGROUND AND AIM Randomised trials indicate that stroke unit care reduces morbidity and mortality after stroke. Similar results have been seen in observational studies but many have not corrected for selection bias or independent predictors of outcome. We evaluated the effect of stroke unit compared with general ward care on outcomes after stroke in(More)
Forthcoming in The Philosophers' Imprint 1. Introduction Let us agree that everything that there is exists, and that to be, to be real, and to exist are one and the same. Does everything that there is exist to the same degree? Or do some things exist more than others? Are there gradations of being? Perhaps no view is more despised by analytic metaphysicians(More)
BACKGROUND Progression is believed to be a common and important complication in acute stroke, and has been associated with increased mortality and morbidity. Reliable identification of predictors of early neurological deterioration could potentially benefit routine clinical care. The aim of this study was to identify predictors of early stroke progression(More)
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