Learn More
This study aimed to determine whether: (a) isometric handgrip (IHG) training lowers resting blood pressure (BP), (b) cardiovascular reactivity to a serial subtraction (SST), IHG (IHGT), and cold pressor (CPT) task predicts this hypotensive response, and (c) cardiovascular reactivity is attenuated posttraining. Resting BP and cardiovascular reactivity to a(More)
Isometric handgrip (IHG) training lowers resting blood pressure (BP) in both hypertensives and normotensives, yet the effect of training dose on the magnitude of reduction and the mechanisms associated with the hypotensive response are elusive. We investigated, in normotensive women, the effects of two different doses of IHG training on resting BP, and(More)
Isometric resistance training has repeatedly shown to be an effective exercise modality in lowering resting blood pressure (BP), yet associated mechanisms and sex differences in the response to training remain unclear. Exploration into potential sex differences in the response to isometric resistance training is necessary, as it may allow for more optimal(More)
The sympathetic nervous system represents a fundamental homeostatic system that exerts considerable control over blood pressure and the distribution of blood flow. This process has been referred to as neurovascular control. Overall, the concept of neurovascular control includes the following elements: efferent postganglionic sympathetic nerve activity,(More)
This exploratory study assessed the pattern of closed-loop baroreflex resetting using multi-logistic-curve analysis. Operating point gain and ranges of RR-interval (RRI) and systolic blood pressure (SBP) are derived to examine how these relate to sympathetic activation. Sustained low-intensity isometric handgrip exercise, with a period of post-exercise(More)
Coronary artery disease affects cortical circuitry associated with brain-heart integration during volitional exercise. study tested the hypothesis that coronary artery disease (CAD) alters the cortical circuitry associated with exercise. Observations of changes in heart rate (HR) and in cortical blood oxygenation level-dependent (BOLD) images were made in(More)
This study tested the hypothesis that neural coding patterns exist within the autonomic nervous system. We investigated sympathetic axonal recruitment strategies in humans during chemoreflex- and baroreflex-mediated sympathoexcitation using a novel action potential (AP) analysis technique. Muscle sympathetic nerve activity (microneurography) was collected(More)
33 This study tested the hypothesis that neural coding patterns exist within the autonomic nervous 34 system. We investigated sympathetic axonal recruitment strategies in humans during 35 chemoreflexand baroreflex-mediated sympathoexcitation using a novel action potential (AP) 36 analysis technique. Muscle sympathetic nerve activity (microneurography) was(More)
This study tested the hypothesis that coronary artery disease (CAD) alters the cortical circuitry associated with exercise. Observations of changes in heart rate (HR) and in cortical blood oxygenation level-dependent (BOLD) images were made in 23 control subjects [control; 8 women; 63 ± 11 yr; mean arterial pressure (MAP): 90 ± 9 mmHg] (mean ± SD) and 17(More)
The objective of this thesis was to replicate findings that isometric handgrip (IHG) training lowers resting blood pressure (BP), determine whether cardiovascular reactivity to a serial subtraction task (SST), IHG task (IHGT), and cold-pressor task (CPT) predict the post-IHG training hypotensive response in hypertensives, and investigate whether(More)