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  • Dongeun Yong, Mark A. Toleman, +4 authors Timothy R. Walsh
  • Biology, Medicine
  • Antimicrobial Agents and Chemotherapy
  • 2009 (First Publication: 21 September 2009)
  • ABSTRACT A Swedish patient of Indian origin traveled to New Delhi, India, and acquired a urinary tract infection caused by a carbapenem-resistant Klebsiella pneumoniae strain that typed to theExpand
  • Karthikeyan K Kumarasamy, Mark A. Toleman, +28 authors Neil Woodford
  • Medicine
  • The Lancet. Infectious diseases
  • 2010 (First Publication: 1 September 2010)
  • Summary Background Gram-negative Enterobacteriaceae with resistance to carbapenem conferred by New Delhi metallo-β-lactamase 1 (NDM-1) are potentially a major global health problem. We investigatedExpand
  • Timothy R. Walsh, Janis Lesley Weeks, David M. Livermore, Mark A. Toleman
  • Biology, Medicine
  • The Lancet. Infectious diseases
  • 2011 (First Publication: 1 May 2011)
  • BACKGROUND Not all patients infected with NDM-1-positive bacteria have a history of hospital admission in India, and extended-spectrum β-lactamases are known to be circulating in the IndianExpand
  • Mark A. Toleman, Alan M. Simm, +4 authors Timothy R. Walsh
  • Biology, Medicine
  • The Journal of antimicrobial chemotherapy
  • 2002 (First Publication: 1 November 2002)
  • The gene encoding the metallo-beta-lactamase SPM-1 was cloned from a genomic library of Pseudomonas aeruginosa strain 48-1997 A. The insert carrying spm-1 possessed a GC content of 47%, indicatingExpand
  • Mariana Castanheira, Mark A. Toleman, Ronald Jones, Franz J. Schmidt, Timothy R. Walsh
  • Biology, Medicine
  • Antimicrobial Agents and Chemotherapy
  • 2004 (First Publication: 1 December 2004)
  • ABSTRACT As part of the SENTRY Antimicrobial Surveillance Program in 2002, five multidrug-resistant Pseudomonas aeruginosa clinical isolates were detected with metallo-β-lactamase (MβL) activity. TheExpand
  • Hélio Silva Sader, Mariana Castanheira, Rodrigo Elisandro Mendes, Mark A. Toleman, Timothy R. Walsh, Ronald Jones
  • Biology, Medicine
  • International journal of antimicrobial agents
  • 2005
  • Carbapenem resistance among Pseudomonas aeruginosa and Acinetobacter spp. is becoming a critical therapeutic problem worldwide. The SENTRY Antimicrobial Surveillance Program monitors pathogenExpand