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  • C. Charlier, W. Coppieters, +8 authors M. Georges
  • 1995
While the hereditary nature of the “double-muscling” phenotype (a generalized muscular hypertrophy documented in several cattle breeds) is well established, its precise segregation mode has remained controversial. Both monogenic models (autosomal dominant or recessive) and oligogenic models have been proposed. Using a panel of 213 bovine microsatellite(More)
Two methods for on-line biomass measurement were tested with success: (a) infrared (IR) estimation of cell components (glucosamine and ergosterol) and medium residues (sucrose and nitrogen) directly on solid medium; (b) the CO2 evolution rate during cultivation. These methods were very satisfactory for following biomass changes during a defined process. The(More)
Haemoptysis is a serious symptom with various aetiologies. Our aim was to define the aetiologies, outcomes and associations with lung cancer in the entire population of a high-income country.This retrospective multicentre study was based on the French nationwide hospital medical information database collected over 5 years (2008-2012). We analysed(More)
BACKGROUND Central sleep apnea (CSA) occurs in clinical situations that induce hypocapnia and respiratory instability during sleep. This is true, not only in heart failure patients, but also in patients suffering from neurological diseases and idiopathic CSA. Adaptive Servo Ventilation (ASV) is frequently prescribed in France for the treatment of CSA, but(More)
BACKGROUND Familial juvenile glomerulonephropathy (JGN) is reported in several breeds of dogs. The mode of inheritance and spectrum of pathological lesions vary among breeds. A progressive JGN was detected in a pedigree of French Mastiff (FM) dogs. OBJECTIVES To describe clinical, laboratory, and histopathologic findings in related FM dogs suffering from(More)
BACKGROUND Measurement of plasma concentration of natriuretic peptides (NPs) is suggested to be of value in diagnosis of cardiac disease in dogs, but many factors other than cardiac status may influence their concentrations. Dog breed potentially is 1 such factor. OBJECTIVE To investigate breed variation in plasma concentrations of pro-atrial natriuretic(More)
  • C. Charlier, B. Denys, +6 authors M. Georges
  • 1996
In the Belgian Blue Cattle breed, coat color variation is mainly under the influence of a single autosomal locus, the roan locus, characterized by a pair of codominant alleles: r+ (black) and R (white). Heterozygous r + R animals have intermingled black and white hairs, yielding the “blue” phenotype typical of the breed. Major interest for the roan locus(More)
Inflammatory Bowel Disease, Crohn's disease and ulcerative colitis, are complex, multifactorial, polygenic diseases. Huge progresses in the knowledge of human genome and genotyping techniques have allowed the identifications of dozens of genes and loci associated with these diseases. These discoveries set the path for a new molecular classification of these(More)
We examined the changes in three biomass constituents (glucosamine, ergosterol, total sugar), sucrose consumption and conidia formation, during cultivation of Beauveria bassiana on agar plates or clay granules. We showed that glucosamine can be considered a good biomass indicator on condition that the media had the same constituents but not necessarily the(More)
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease causing diaphragm weakness that can be partially compensated by inspiratory neck muscle recruitment. This disappears during sleep, which is compatible with a cortical contribution to the drive to breathe. We hypothesised that ALS patients with respiratory failure exhibit respiratory-related(More)