Marjana Khalil

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The pharmacokinetics and maternal and neonatal effects of epidural lidocaine were compared in ten preeclamptic and five normotensive women undergoing cesarean section at 36-40 weeks of gestation. Lumbar epidural anesthesia was achieved using 15-20 ml of 2% lidocaine without epinephrine. Serial venous samples for lidocaine levels were drawn from all the(More)
To determine the effect of liver cirrhosis on the pharmacokinetics and pharmacodynamics of pipecuronium, the authors administered 100 micrograms/kg of pipecuronium intravenously to eight patients with liver cirrhosis and eight patients with normal liver and renal function undergoing elective abdominal surgery. All patients were anesthetized with thiopental(More)
BACKGROUND Rocuronium, like other steroidal nondepolarizing muscle relaxants, may in part be eliminated by the liver. To determine the influence of liver disease on its neuromuscular blocking effect, we studied the pharmacokinetics and pharmacodynamics of rocuronium in patients with cirrhosis. METHODS Eighteen patients undergoing elective surgery, 10 with(More)
We compared in a randomized double-blind study, the postoperative analgesia and degree of motor block produced by the new local anaesthetic ropivacaine, with bupivacaine, for caudal anaesthesia in children. Eighty children, 2-5-years-old, ASA I, received one of two local anaesthetics; either ropivacaine 0.25% (1.0 ml x kg(-1)) or bupivacaine 0.25% (1.0 ml x(More)
In a controlled, randomized study, we evaluated duration of neuromuscular block in 80 patients undergoing routine abdominal surgery. Forty patients were aged 18-50 yr (control group) and 40 patients were more than 65 yr (elderly group). All patients had normal plasma creatinine concentrations. After induction of anaesthesia, patients were allocated randomly(More)
Arjunarista (RJN) is an Ayurvedic preparation used as a traditional medicine in the south Asian countries for the treatment of cardiac diseases. We were eager to know the effect of chronic administration of RJN on the lipid profile test. To find out the effect of chronic administration of RJN on the lipid profile it was administered chronically to the male(More)
Balarista (BLR) is an Ayurvedic preparation used as a traditional medicine in the South Asian countries for the treatment of dyspepsia, debility and arthritis. The effect of chronic administration of Balarista (BLR) on the serum Lipid profile was studied in this experiment. After 28 days of chronic administration of the BLR preparation to the male(More)
Rohitakarista (RHT) is an Ayurvedic preparation used as a traditional medicine in the South Asian countries for the treatment of liver disorders, splenomegaly and other spleen related problems. The effect of chronic administration of Rohitakarista on the hematological parameters and serum iron profile was studied in this experiment. The acute toxicity test(More)
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