Marjaana Nousiainen

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OBJECTIVE We performed a clinical study in 99 children attending schools with moisture problems and compared the findings with those of 34 children from a reference school. The aim of the study was to evaluate the possible association between respiratory or allergic diseases in the pupils and moisture or mould problems in the school buildings. RESULTS(More)
Synthetic RS20 peptide and a set of its point-mutated peptide analogs have been used to analyze the interactions between calmodulin (CaM) and the CaM-binding sequence of smooth-muscle myosin light chain kinase both in the presence and the absence of Ca(2+). Particular peptides, which were expected to have different binding strengths, were chosen to address(More)
Electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry was used to investigate Ca(2+), Mg(2+), and La(3+) binding to bovine bone osteocalcin (OCN). OCN was shown to bind 3 mol Ca(2+) per mol protein. There was also evidence for the presence of four additional metal binding sites. Ca(2+) increased the formation of the OCN dimer.(More)
Chlorophenols (CPs) as persistent toxic compounds are of worldwide environmental concern. Usage of chlorinated phenols, especially pentachlorophenol (PCP), has been restricted or widely banned in many countries due to their possible adverse health effects even at low concentrations. Ion mobility spectrometry (IMS) has received increasing interest in(More)
In recent years, explosive materials have been widely employed for various military applications and civilian conflicts; their use for hostile purposes has increased considerably. The detection of different kind of explosive agents has become crucially important for protection of human lives, infrastructures, and properties. Moreover, both the environmental(More)
OBJECTIVE To determine the influence of the number of cortices of fixation on the stiffness of plate fixation of diaphyseal fractures. DESIGN Canine experimental study. SETTING Tertiary referral and teaching hospital in Toronto, Canada. PARTICIPANTS Paired radii from fourteen skeletally mature, cross-bred dogs. MAIN OUTCOME MEASURE One member of(More)
Aspiration ion mobility spectrometry (IMS) has been used for the first time to screen 3,3,6,6,9,9-hexamethyl-1,2,4,5,7,8-hexaoxacyclononane explosive, the most commonly known as triacetone triperoxide (TATP). Gaseous TATP was generated from synthesized solid compound, sublimed and directed to a portable chemical detection system comprised of an(More)
Ion mobility spectrometry (IMS) is an instrumental technique used successfully for the detection of wide range of organic compounds in the gas phase. In this paper, advances in using special substances called dopants for gases flowing through IMS detectors are reviewed. These substances influence the ion-molecule chemistry in sample ionisation region as(More)
Ethyl parathion and toluene 2,4-diisocyanate (2,4-TDI) vapors were generated using a vapor generation system that was designed for the evaporation of liquid samples at known flow rates. The vapor generation of parathion and 2,4-TDI posed a challenge because of their low volatility and tendency to absorb into surfaces of the vapor generation system.(More)
Fuel oxygenates are environmentally detrimental compounds due to their rapid migration to groundwater. Fuel oxygenates have been reported to cause taste and odour problems in drinking water, and they also have long-term health effects. Feasible analytical methods are required to observe the presence of fuel oxygenates in drinking and natural water. The(More)