Mariusz Dubiel

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About half of all fetuses with increased resistance to blood flow, but with still detectable diastolic blood velocity in the umbilical artery (UA), show signs of imminent asphyxia during labour indicating a need for operative delivery. Fetal brain-sparing during hypoxia is characterized by an increase in diastolic and mean blood flow velocity in the middle(More)
OBJECTIVE Uterine artery Doppler is becoming a routine part of pregnancy surveillance in high-risk pregnancies. Which blood flow velocity waveform index to measure is debated and the 'notch' in early diastole is not widely accepted, as it is a subjective measure. The aim of the present study was to evaluate the different indices in the prediction of adverse(More)
OBJECTIVE Signs of increased uterine artery vascular impedance in mid-gestation are strongly related to pre-eclampsia later in pregnancy. Whether this is true for the late third trimester is, however, unclear. The aim of the present study was to analyze the frequency of increased uterine artery vascular impedance in the third trimester, and its relationship(More)
Three-dimensional (3-D) ultrasound imaging has improved evaluation of organ circulation and might contribute new information on maternal and fetal blood supply. Flow index (FI) of 3-D color images has been proposed as a measure of perfusion. The aim of this study was to evaluate whether the 3-D FI is a parameter of volume flow and flow velocity in a human(More)
BACKGROUND Doppler ultrasound examination has become an established method of clinical surveillance in high-risk pregnancies. Doppler indication of fetal brain sparing (BS) is an acknowledged sign of circulation redistribution during chronic hypoxia. OBJECTIVES To evaluate the relationship between placental vascular resistance and signs of BS in middle(More)
OBJECTIVE We sought to establish references ranges and to test the hypothesis that biochemical tissue-specific markers for the heart in umbilical cord blood of newborns with cardiac defects and intrauterine growth restriction (IUGR) are abnormal. STUDY DESIGN A prospective study was conducted. Serum samples of the umbilical vein (n = 280) and artery (n =(More)
BACKGROUND Impaired trophoblast invasion is suggested as the main cause of reduced placental perfusion, which results in fetal growth restriction and preeclampsia. Immunological response against the invading tissue has been given as the explanation. Preeclampsia frequently recurs during the next pregnancy. Doppler ultrasound can predict increased vascular(More)
Because fetal motor activity reflects the fetal condition in utero, maternal counting of fetal movements has been suggested as a useful method for monitoring fetal well-being, based on empirical evidence that a decrease in or absence of fetal movements often presages fetal death. The aim of this study was to compare the predictive capacity of umbilical(More)
Growth factors as vascular endothelial growth factor (VEGF), produced by the endothelial cells, take an essential part in pathological and physiological angiogenesis. The possibility of angiogenesis modulation by application of laser radiation may contribute to the improvement of its use in this process. Thus, the aim of the study was to investigate the(More)
OBJECTIVES Estimation of oxidative stress through the measurement of lipid peroxides and malondialdehyde serum concentration as well as serum antioxidants level expressed by total antioxidants status and its correlation with Doppler velocimetry in women with preeclampsia. MATERIAL AND METHODS Thirty four patients with preeclampsia at third trimester of(More)