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Programmed cell death in the developing somites is promoted by nerve growth factor via its p75(NTR) receptor.

• Maria Luisa Cotrina, Maritza González-Hoyuela, Julio A. Barbas, Alfredo Rodríguez-Tébar
• Developmental biology
• 2000

Neurotrophins control neuron number during development by promoting the generation and survival of neurons and by regulating programmed neuronal death. In the latter case, the cell death induced by… (More)

The autoregulation of retinal ganglion cell number.

• Maritza González-Hoyuela, Julio A. Barbas, Alfredo Rodríguez-Tébar
• Development
• 2001

The development of the nervous system is dependent on a complex set of signals whose precise co-ordination ensures that the correct number of neurones are generated. This regulation is achieved… (More)

[Indicators of oxidative stress in aging rat brain. The effect of nerve growth factor].

• Karina Rodríguez-Capote, E. I. Cespedes, Ricardo Arencibia, Maritza González-Hoyuela
• Revista de neurologia
• 1998

INTRODUCTION AND OBJECTIVE Increased oxidative stress during ageing and the neurodegenerative disorders associated with this has been described. The central nervous system is particularly vulnerable… (More)

[Genetic expression of nerve growth factor in the central nervous system. Evaluation of an experimental model for Alzheimer's dementia].

• Maritza González-Hoyuela, Julián Soto, Rolando Garcia-Milian, Raimundo Ubieta, Leo P. Francis, R Conde-Vázquez
• Revista de neurologia
• 1998

INTRODUCTION AND OBJECTIVE Several authors have suggested that loss of neuronal trophic support may be an important element in the physiopathology of degenerative conditions of the central nervous… (More)

Pathogenic mutations in the 5' untranslated region of BCS1L mRNA in mitochondrial complex III deficiency.

• Mari Carmen Gil-Borlado, Maritza González-Hoyuela, +8 authors Cristina Ugalde
• Mitochondrion
• 2009

Mutations in the assembly chaperone BCS1L constitute a major cause of mitochondrial complex III deficiency. We studied the presence of BCS1L mutations in a complex III-deficient patient with… (More)

[Oxidative stress in neurodegeneration].

• Ma Elena González-Fraguela, O Castellano-Benítez, Maritza González-Hoyuela
• Revista de neurologia
• 1999

INTRODUCTION The aetiology of the neuronal death which occurs in neurodegenerative diseases is still unknown. These disorders are of insidious onset and follow an inexorable, gradually progressive… (More)

[Genetic therapy for the nervous system: a trend in modern neurology].

• Maritza González-Hoyuela, Ma Elena González-Fraguela
• Revista de neurologia
• 1998

INTRODUCTION Genetic therapy is in itself a new type of treatment, of potential use in many neurological conditions currently considered to be resistant to conventional treatment. Great advances have… (More)

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