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To assess the spatio-temporal structure of discontinuous EEG tracing in mature and immature newborns, we analysed mean spectral power in frequency bands between 0.8 and 16.8 Hz in 6 full-term newborns and 7 premature newborns < 32 weeks of conceptional age. The most striking results showed a significantly higher mean spectral power for the first half of(More)
STUDY DESIGN For in vitro studies, there is no basis for choosing a "load control study" over a "displacement control" study. This study qualitatively compared results from in vitro and in vivo tests, allowing the authors to address the experimental assumptions that in vitro testing contributes to the understanding of the in vivo condition. OBJECTIVES To(More)
The motion and facet load changes at the adjacent segment after lumbosacral immobilization (with different angles) were quantified in vitro using canine spines. Changes were examined under flexion, extension, and lateral bending. An increase (extension: 62%; flexion: 85%; left bend: 30%; right bend 26%) in motion at the adjacent segment was found for all(More)
Long levels of spinal instrumentation and fusion are common in surgery for spinal deformity. The effect on the remaining mobile segments is not well understood. The changes in lumbar facet loading and lumbosacral motion were evaluated as the number of immobilized levels increased. Four fresh canine cadaveric spines from T6 to sacrum were used. Lumbosacral(More)
Although the normal sagittal profile of the thoracolumbar spine has been described, this has been obtained primarily by using young individuals standing. We sought to describe the sagittal profile of the thoracolumbar spine in an older population in the supine cross-table lateral position compared with that standing. We enrolled 50 volunteers with no(More)
Fixation to the sacrum and pelvis is a problem in the operative treatment of spinal deformity. Previous testing of pedicle screws address axial pull-out strength, yet how screws are loaded in vivo remains unknown. The goals of this study were to determine the loads experienced by sacral screws when loaded as part of Cotrel-Dubousset (CD) sacral(More)
We describe an enzyme-linked immunosorbent assay (ELISA) for quantifying relative amounts of active caspase 3 in apoptotic cells. Covalent modification of caspase 3 active sites with a biotinylated inhibitor differentiates active from latent caspases. Capture on an ELISA plate with an antibody specific for caspase 3 makes the assay specific for caspase 3.(More)
STUDY DESIGN Eighteen patients with adolescent idiopathic scoliosis treated with ISOLA instrumentation and 13 treated with Cotrel-Dubousset instrumentation were studied before and after surgery with computed tomography scans. OBJECTIVES To analyze and compare the immediate change in chest volume of patients treated with the derotation method of(More)