Marisol Veny

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BACKGROUND Th1 and Th17 cells have been implicated in Crohn's disease (CD) pathophysiology and may play a role in disease persistence. Aim To determine Th1 and Th17 responses in intestine and peripheral blood of early (<32 weeks since initial symptoms) and late (>2 years) CD patients. METHODS Cytokine mRNA in intestinal biopsies was determined by RT-PCR.(More)
Loss of tolerance toward commensal bacteria has been invoked as a mechanism for Crohn's disease. IL-10 is a key anti-inflammatory cytokine that plays a role in induction and maintenance of tolerance. The aim of this study is to determine IL-10 production in response to bacterial components in Crohn's disease patients, who were classified according to their(More)
eply. We thank Dr Shah for her appreciation of our tudy and acceptance of our results. We agree that furher, well-designed, randomized, controlled trials are eeded to confirm our results. A recent study in adults Am J Gastroenterol 2010 Jun 1 [Epub ahead of print]) nd 2 studies in children (Inflamm Bowel Dis 2009;15: 60 –768; Am J Gastroenterol(More)
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