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—Several recent publications have shown that joint source-channel decoding could be a powerful technique to take advantage of residual source redundancy for fixed-and variable length source codes. This letter gives an in-depth analysis of a low-complexity method recently proposed by Guivarch et al., where the redundancy left by a Huffman encoder is used at(More)
Mechanical forces including gravity affect endothelial cell (ECs) function, and have been implicated in vascular disease as well as physiologic changes associated with low gravity environments. The goal of this study was to investigate the impact of gravitational mechanical unloading on ECs phenotype as determined by patterns of gene expression. Human(More)
Ammonium (NH4+ and/or NH3) and K+ are released from active neurons and taken up by glial cells, and can modify glial cell behaviour. Study of these fluxes is most advanced in the retina of the honeybee drone, which consists essentially of identical neurons (photoreceptors) and identical glial cells (outer pigment cells). In isolated bee retinal glial cells,(More)
OBJECTIVE Mutations in the type IV collagen alpha 1 gene (COL4A1) cause dominantly inherited cerebrovascular disease. We seek to determine the extent to which COL4A1 mutations contribute to sporadic, nonfamilial, intracerebral hemorrhages (ICHs). METHODS We sequenced COL4A1 in 96 patients with sporadic ICH. The presence of putative mutations was tested in(More)
Collagen, type IV, alpha 1 (COL4A1) and alpha 2 (COL4A2) form heterotrimers and are abundant components of basement membranes, including those of the cerebral vasculature. COL4A1 mutations are an increasingly recognized cause of multisystem disorders, including highly penetrant cerebrovascular disease and intracerebral hemorrhage (ICH). Because COL4A1 and(More)
Several recent publications have shown that joint source-channel decoding (JSCD) could be a powerful technique for taking advantage of residual source redundancy. Furthermore, it appeared that the principle could also be successfully applied to variable length codes (VLCs). This paper gives an in-depth analysis of a new method recently proposed in [1], [2](More)
BACKGROUND Collagen type IV alpha1 (COL4A1) and alpha2 (COL4A2) form heterotrimers critical for vascular basement membrane stability and function. Patients with COL4A1 or COL4A2 mutations suffer from diverse cerebrovascular diseases, including cerebral microbleeds, porencephaly, and fatal intracerebral hemorrhage (ICH). However, the pathogenic mechanisms(More)
Collagen type IV alpha 1 and 2 (COL4A1 and COL4A2) are present in nearly all basement membranes. COL4A1 and COL4A2 mutations are pleiotropic, affecting multiple organ systems to differing degrees, and both genetic-context and environmental factors influence this variable expressivity. Here, we report important phenotypic and molecular differences in an(More)
This paper describes the application of a joint source channel decoding technique (JSCD) of variable length codes (VLCs), presented at first by Guiv-arch et al., in the context of future public land mobile telecommunication systems (FPLMTS) involving UMTS channel codes and OFDM modulation. OFDM parameter sets have been adjusted both to the UMTS chip rate(More)