Marion Behrens

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Fatigue is a common symptom in multiple sclerosis (MS) patients, even early in the disease, but the pathophysiology remains unclear. We aimed to determine morphologic and microstructural correlates and neuropsychological parameters of cognitive fatigue in early relapsing-remitting MS patients. Seventy-nine early relapsing-remitting MS patients (38 with(More)
Human deep sleep is characterized by reduced sensory activity, responsiveness to stimuli, and conscious awareness. Given its ubiquity and reversible nature, it represents an attractive paradigm to study the neural changes which accompany the loss of consciousness in humans. In particular, the deepest stages of sleep can serve as an empirical test for the(More)
Optimizing energy usage in buildings requires global models that integrate multiple factors contributing to energy, such as lighting , " Heating, Ventilating, and Air Conditioning " (HVAC), security, etc. Model transformation methods can then use these global models to generate application-focused code, such as diagnostics or control code. In this paper we(More)
BACKGROUND AND PURPOSE Compensatory and restorative treatments have been developed to improve visual field defects after stroke. However, no controlled trials have compared these interventions with standard occupational therapy (OT). METHODS A total of 45 stroke participants with visual field defect admitted for inpatient rehabilitation were randomized to(More)
This paper presents the principles of concept-driven engineering and the Concept-Manager tool as an implementation of these principles. Concept-Driven Engineering is capable of eleminating inconsistencies and redundancy that occurr within projects, i.e. in the software-development process to increase quality, decrease time to market, and increase(More)
Phonetic detail and lateralization of inner speech during covert sentence reading as well as overt reading in 32 right-handed healthy participants undergoing 3T fMRI were investigated. The number of voiceless and voiced consonants in the processed sentences was systematically varied. Participants listened to sentences, read them covertly, silently mouthed(More)
We previously reported speaking-related activity changes associated with assisted recovery induced by a fluency shaping therapy program and unassisted recovery from developmental stuttering (Kell et al., Brain 2009). While assisted recovery re-lateralized activity to the left hemisphere, unassisted recovery was specifically associated with the activation of(More)
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