Marion Bartholome

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Apolipoprotein A-I concentration in human serum was determined by kinetic nephelometry. Under optimal reaction conditions and within the normal physiological range the relation between apolipoprotein A-I concentration and measured rate units it approximately linear. The detection limit of the assay lies at 2 micrograms/ml. The coefficient of variation(More)
Sonic hedgehog (SHH) is a conserved protein involved in embryonic tissue patterning and development. SHH signaling has been reported as a cardio-protective pathway via muscle repair-associated angiogenesis. The goal of this study was to investigate the role of SHH signaling pathway in the adult myocardium in physiological situation and after(More)
The aim of the study was to achieve the measurement of lecithin : cholesterol acyltransferase (EC activity independent of and uninfluenced by equilibration of lipids between different lipoproteins, their molar ratios or by possible differences in their substrate quality. A mixture of sodium phosphotungstic acid/MgCl2 was added to serum samples to(More)
Thirty-one serum and CSF samples from 21 HIV-antibody-positive patients with neurological deficits were examined to prove or exclude intrathecal production of HIV antibodies. By dilution, sera were adjusted to the IgG concentration of the corresponding CSF samples. Both samples were then serially diluted in log2 steps down to the detection limit and were(More)
A method is described for the enzymatic determination of the cholesterol content of serum lipoproteins separated by electrophoresis on agarose. The method shows high precision and correlated well with quantiative lipoprotein electrophoresis based on polyanion precipitation.
An experiment conducted at the University of Liège, Belgium in the computer-assisted teaching of juvenile-type insulin-dependent diabetics is reported. The course was designed to individualize teaching in order to give a minimum of basic information to a maximum of patients. The original computer-assisted instruction system DOCEO II is described; methods(More)
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