Marion A. Hofmann Bowman

  • Citations Per Year
Learn More
Arterial inflammation is the consequence of an orchestrated response of cells within the arterial wall to multifactorial modes of injury; arterial inflammation is a fundamental mechanism contributing to atherosclerosis and restenosis. The remodeling of the arterial wall that results from the inflammation could either be obstructive (as in coronary and(More)
Atherosclerosis is mediated by local and systematic inflammation. The multiligand receptor for advanced glycation end products (RAGE) has been studied in animals and humans and is an important mediator of inflammation and atherosclerosis. This review focuses on S100/calgranulin proteins (S100A8, S100A9, and S100A12) and their receptor RAGE in mediating(More)
With an estimated 17.5 million deaths yearly, cardiovascular diseases remain the leading cause of death in the world. Atherosclerosis is a chronic inflammatory process of the vascular wall mediated by activated macrophages, T lymphocytes, B lymphocytes, and smooth muscle cells (SMC). Accordingly, multiple inflammatory serum markers have been investigated(More)
Airway inflammation, lung remodeling, and Airway Hyperresponsiveness (AHR) are major features of asthma and Chronic Obstructive Pulmonary Disease (COPD). The inflammatory response to allergens, air pollutants, and other insults is likely to play a key role in promoting structural changes in the lung including the overabundance of Airway Smooth Muscle (ASM)(More)
  • 1