Marion A. Hofmann Bowman

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OBJECTIVES The purpose of this study was to determine the relevance of S100A12 expression to human thoracic aortic aneurysms and type A thoracic aortic aneurysm dissection and to study mechanisms of S100A12-mediated dysfunction of aortic smooth muscle cells. BACKGROUND Transgenic expression of proinflammatory S100A12 protein in murine aortic smooth muscle(More)
Arterial inflammation is the consequence of an orchestrated response of cells within the arterial wall to multifactorial modes of injury; arterial inflammation is a fundamental mechanism contributing to atherosclerosis and restenosis. The re-modeling of the arterial wall that results from the inflammation could either be obstructive (as in coronary and(More)
Identification of the direct spinal areas (portions of the dorsal and medial accessory nuclei) within the opossum inferior olivary complex was accomplished by mapping the location of the terminal degeneration by the Fink-Heimer technique subsequent to cervical cord lesions. Following similar lesions, sampling of these same regions for electron microscopic(More)
Airway inflammation, lung remodeling, and Airway Hyperresponsiveness (AHR) are major features of asthma and Chronic Obstructive Pulmonary Disease (COPD). The inflammatory response to allergens, air pollutants, and other insults is likely to play a key role in promoting structural changes in the lung including the overabundance of Airway Smooth Muscle (ASM)(More)
fresh account of the original discoveries and their development in Great Britain, Switzerland, and the United States. Your reviewer found the French text very easy to follow, illuminating about the qualities which make research succesful, informative, and humorous. Some minor inaccuracies, especially in English names and in the initials of authors, are more(More)
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