Marion A. Cooley

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laxa Homozygosity for a missense mutation in fibulin-5 (FBLN5) results in a severe form of cutis integrative aspects of normal and abnormal function of cells and components of the respiratory system. It is published 12 times a publishes original research covering the broad scope of molecular, cellular, and
BACKGROUND Cubilin is a peripheral membrane protein that interacts with the integral membrane proteins megalin and amnionless to mediate ligand endocytosis by absorptive epithelia such as the extraembryonic visceral endoderm (VE). RESULTS Here we report the effects of the genetic deletion of cubilin on mouse embryonic development. Cubilin gene deletion is(More)
To meet demands of vascular reconstruction, there is a need for prosthetic alternatives to natural blood vessels. Here we explored a new conduit fabrication approach. Macroporous, gelatin microcarriers laden with human umbilical vein endothelial cells and aortic smooth muscle cells were dispensed into tubular agarose molds and found to adhere to form living(More)
Endothelial to mesenchymal transition (EMT) that occurs during cardiac outflow tract (OFT) development is critical for formation of the semilunar valves. Fibulin-1 (Fbln1) is an extracellular matrix protein that is present at several sites of EMT, including the OFT (i.e., E9.5-10.5). The aim of this study was to determine the role of Fbln1 in EMT during the(More)
myofibroblasts FGF-18 is upregulated in the postnatal rat lung and enhances elastogenesis in including high-resolution figures, can be found at: Updated information and services integrative aspects of normal and abnormal function of cells and components of the respiratory system. It is published 12 times a publishes original research covering the broad(More)
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