Mario Senden

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Brain function relies on the flexible integration of a diverse set of segregated cortical modules, with the structural connectivity of the brain being a fundamentally important factor in shaping the brain's functional dynamics. Following up on macroscopic studies showing the existence of centrally connected nodes in the mammalian brain, combined with the(More)
Resting state networks (RSNs) show a surprisingly coherent and robust spatiotemporal organization. Previous theoretical studies demonstrated that these patterns can be understood as emergent on the basis of the underlying neuroanatomical connectivity skeleton. Integrating the biologically realistic DTI/DSI-(Diffusion Tensor Imaging/Diffusion Spectrum(More)
Despite the absence of stimulation or task conditions the cortex exhibits highly structured spatio-temporal activity patterns. These patterns are known as resting state networks (RSNs) and emerge as low-frequency fluctuations (<0.1 Hz) observed in the fMRI signal of human subjects during rest. We are interested in the relationship between structural(More)
The interactions of Cd2+ with active Ca2+ transport systems in rat intestinal epithelial cells have been investigated. ATP-driven Ca2+ transport in basolateral plasma membrane vesicles was inhibited by Cd2+ with an I50 value of 1.6 nM free Cd2+ at 1 microM free Ca2+, using EGTA and HEEDTA to buffer Ca2+ and Cd2+ concentrations, respectively. The inhibition(More)
Major amino acids and organic acids in xylem exudates of tomato plants were separated by reversed phase high performance liquid chromatography (RP-HPLC) and quantified by UV detection. Before separation, amino acids were converted into their phenylisothiocyanate (PITC) derivatives. In a single run, Asp, Glu, Ser, Gln, His, Thr, Ala, Tyr, Val, Met, Cys, Ile,(More)
Experiments were carried out to investigate the effects of root citric acid on uptake and initial distribution of cadmium (Cd) in tomato plants (Lycopersicon esculentum, cv. Tiny Tim). Cd was measured by γ-spectrometry, using 115Cd spikes. Citric acid was measured by UV-detection, and, after spiking with 14C-citric acid, by β-spectrometry. Cd was applied(More)
Within vision research retinotopic mapping and the more general receptive field estimation approach constitute not only an active field of research in itself but also underlie a plethora of interesting applications. This necessitates not only good estimation of population receptive fields (pRFs) but also that these receptive fields are consistent across(More)
Cognition is hypothesized to require the globally coordinated, functionally relevant integration of otherwise segregated information processing carried out by specialized brain regions. Studies of the macroscopic connectome as well as recent neuroimaging and neuromodeling research have suggested a densely connected collective of cortical hubs, termed the(More)
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