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OBJECTIVE To study the influence of body mass index (BMI), smoking, and age on the risk of vaginal erosions after mesh repair of pelvic prolapses. DESIGN Retrospective study. SETTING Three university and community hospitals. POPULATION AND SAMPLE Patients that underwent mesh correction of prolapses between 2002 and 2007. Excluded were those with(More)
OBJECTIVE To compare the intraoperative and immediate postoperative results achieved with the tension-free vaginal tape Secur (TVT-S) hammock procedure performed under local anesthesia (LA) versus general anesthesia (GA). METHODS Prospective randomized trial involving patients with symptomatic stress urinary incontinence grades 1 or 2 who underwent TVT-S(More)
The role of cancer stem cells (CSC) in tumour growth has received increasing attention in the recent literature. Here we stem from an integro-differential system describing the evolution of a population of CSC and of ordinary (non-stem) tumour cells formulated and studied in a previous paper, and we investigate an approximation in which the system reduces(More)
Received (Day Month Year) Revised (Day Month Year) Communicated by (xxxxxxxxxx) We consider a convection-diffusion problem in a porous medium saturated by a solution of a chemical substance A in water. A nonlinear non-equilibrium kinetics of sorp-tion/desorption of A on the porous matrix is assumed. We assume that the chemical substance can be transported(More)
The tumour growth paradox refers to the observation that incomplete treatment of cancers can enhance their growth. As shown here and elsewhere, the existence of cancer stem cells (CSCs) can explain this effect. CSC are less sensitive to treatments, hence any stress applied to the tumour selects for CSC, thereby increasing the fitness of the tumour. In this(More)