Mario Nava-Villalba

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An iodinated derivative of arachidonic acid, 5-hydroxy-6-iodo-8,11,14-eicosatrienoic acid, δ-lactone (6-IL) has been implicated as a possible intermediate in the autoregulation of the thyroid gland by iodine. In addition to antiproliferative and apoptotic effects observed in thyrocytes, this iodolipid could also exert similar actions in cells derived from(More)
Two cases of leiomyomatous hamartoma (LH) in patients of Latin ancestry are reported here. The first lesion was detected on the incisive papilla of a 19-year-old woman; this is an unusual age because these lesions are commonly observed during the first years of life. The second lesion found on the middle-dorsum of the tongue was observed in a 5-month-old(More)
Molecular iodine (I2) exhibits antiproliferative and apoptotic effects on in vivo and in vitro cancer models. These effects are thought to be mediated by an iodinated arachidonic acid derivative, 6-iodolactone (6IL), and one of the proposed mechanisms is that 6IL activates Peroxisome Proliferator-Activated Receptors type gamma (PPARG). These receptors have(More)
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