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  • Margot Fonteyne, J Arruabarrena, +6 authors Thomas de Beer
  • Medicine, Chemistry
  • Journal of pharmaceutical and biomedical analysis
  • 1 November 2014
  • This study focuses on the thorough validation of an in-line NIR based moisture quantification method in the six-segmented fluid bed dryer of a continuous from-powder-to-tablet manufacturing lineContinue Reading
  • Anneleen Burggraeve, Tom Van den Kerkhof, Mario Hellings, Jean Paul Remon, Chris Vervaet, Thomas de Beer
  • Chemistry, Medicine
  • European journal of pharmaceutical sciences…
  • 1 April 2011
  • Fluid bed granulation is a batch process, which is characterized by the processing of raw materials for a predefined period of time, consisting of a fixed spraying phase and a subsequent dryingContinue Reading
  • Steven Kuppens, Mario Hellings, Jan Jordens, Stefan Verheyden, Yves Engelborghs
  • Chemistry, Medicine
  • Protein science : a publication of the Protein…
  • 1 May 2003
  • The hinge residues (Val29 and Ile36) of the switch I region (also known as the effector loop) of the Ha-ras-p21 protein have been mutated to glycines to accelerate the conformational changes typicalContinue Reading
  • Maxim Verstraeten, Daan Van Hauwermeiren, +5 authors Thomas de Beer
  • Chemistry, Medicine
  • International journal of pharmaceutics
  • 1 July 2018
  • Graphical abstract Figure. No Caption available. &NA; The implementation of Process Analytical Technology (PAT) instruments is generally achieved stochastically. Sub‐optimal PAT locations couldContinue Reading
  • Anneleen Burggraeve, Tom Van den Kerkhof, Mario Hellings, Jean Paul Remon, Chris Vervaet, Thomas de Beer
  • Chemistry, Medicine
  • European journal of pharmaceutics and…
  • 1 September 2010
  • In this study, the feasibility of spatial filter velocimetry (SFV) as process analytical technology tool for the in-line monitoring of the particle size distribution during top spray fluidized bedContinue Reading