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BACKGROUND There are no internationally validated questionnaires to investigate the prevalence of infant wheezing. This study was undertaken to validate a questionnaire for the International Study on the Prevalence of Wheezing in Infants (Estudio Internacional de Sibilancias en Lactantes, EISL). MATERIAL AND METHODS Construct and criterion validity were(More)
Andrographis paniculata (Burm. f.) Wall ex Nees (Acanthaceae) possesses anti-inflammatory effects, attributed to the main constituent andrographolide proposed as alternative in the treatment of autoimmune disease. A prospective, randomized, double blind, and placebo-controlled study in patients with rheumatoid arthritis (RA) was performed. Tablets(More)
The objective of this work was to determine the frequency and clinical associations of anti-ribosomal P protein antibodies (Anti-P) in a cohort of Chilean patients with systemic lupus erythematosus (SLE). Between 1996 and 1998, 141 consecutive patients with SLE were examined prospectively according with a standard protocol. Disease activity was measured by(More)
The role that house dust mites play in the primary causation of asthma is controversial. Approximately thirty-six 10-yr-old children in each of 10 centres in the Asia-Pacific region participated. Researchers collected dust from mattresses and living room floors using standardized procedures. Der p1 and Der f1 were analysed using a double monoclonal antibody(More)
Little is known about hepatitis E virus (HEV) prevalence in South American countries. Anti-HEV was studied in 1,773 subjects from 1,360 blood donors of 3 cities in Chile, 72 in health care workers, 241 inmates in state jails, and in 100 Araucanian indians. Anti-HEV was detected in 109 out of 1,360 (8.0%) total donors (6.3%, 6.1%, and 18.8% from the cities(More)
A procedure for the determination of oxcarbazepine (OXC) by Square Wave Adsorptive Stripping Voltammetry (SWAdSV) has been optimized. Selection of the experimental parameters was made using experimental design methodology. The detection limit was 1.74 x 10(-7) mol dm(-3). This method was used to determine oxcarbazepine in pharmaceutical preparations.
BACKGROUND In developed countries, the prevalence of asthma in children has significantly increased in the last decades. However, there is no information about the trends of asthma in Latin America. AIM To determine changes in asthma prevalence between 1994 and 2002 in Chilean schoolchildren. MATERIAL AND METHODS The prevalence of asthma symptoms in(More)
One hundred consecutive asthmatic paediatric patients were evaluated and skin tested with a battery of skin prick test reagents, including 8 different standardized house dust mite extracts. Asthma severity was graded according to the Global Initiative for Asthma (GINA) document in mild persistent (52 patients), moderate persistent (39) and severe persistent(More)
UNLABELLED Human infection by Streptococcus suis is a zoonosis with a known occupational risk. Meningitis is its most frequent clinical manifestation. We present the first two cases in Chile. FIRST CASE 54-year-old female patient, pig-farmer. She presented headache, vomiting, confusion and meningismus. She presented septic shock. Second case: 48-year-old(More)