Mario Bifani

Learn More
Corneal morphological analysis has greatly improved in recent years, providing physicians with new and reliable parameters to study. Moreover, today corneal functional too is a routine analysis, thanks to biomechanical evaluation allowed by an ocular response analyzer (Reichert Ophthalmic Instrument, Depew, NY, USA). Corvis ST (OCULUS Optikgeräte GmbH,(More)
PURPOSE We studied an Italian family affected by the autosomal dominant form of microcephaly and chorioretinal degeneration that was characterized by various degrees of clinical expression. METHODS An ophthalmologic examination, including visual acuity, visual field testing, an electroretinogram, and fundus photography, and a neurologic examination,(More)
BACKGROUND Intravitreal injection of human mesenchymal stem cells has been shown to be effective in slowing the progression of diabetic retinopathy in an animal model of chemically induced diabetes mellitus. We studied changes in growth factor levels released from human mesenchymal stem cells in the vitreous cavity as well as changes in growth factor levels(More)
This study was designed to evaluate the correlation between corneal biomechanical and morphological data in healthy eyes, eyes that underwent myopic photorefractive keratectomy (PRK), keratoconus affected eyes, and keratoconus affected eyes that underwent corneal collagen crosslinking (CCC). Complete clinical eye examination of all eyes was followed by(More)
PURPOSE To evaluate the correlation between corneal biomechanical and morphological data in healthy eyes. METHODS A complete clinical eye examination of naïve eyes was followed by tomographic (Pentacam, Oculus, Wetzlar, Germany) and biomechanical (Corvis ST, Oculus, Wetzlar, Germany) evaluation. Linear regression between central corneal thickness (CCT),(More)
PURPOSE To compare corneal pachymetry values measured by three different optical devices: Orbscan II, Pentacam HR and Sirius in healthy eyes. METHODS The central corneal thickness (CCT) of 102 eyes of 102 healthy subjects (mean age of 33.09 ± 8.72 years and mean refractive defect -4.11 ± 4.74 D) was measured by three different physicians using Orbscan II,(More)
PURPOSE To describe bilateral corneal alterations through confocal microscopy in a patient affected by Cowden syndrome (CS). METHODS Evaluation of Schirmer's, fluorescein, and lissamine green dye tests. Confocal microscopy was performed in both eyes to investigate corneal abnormalities. RESULTS Slit lamp observation showed the focal involvement of(More)
PURPOSE To analyze and compare intraocular pressure (IOP) values measured in healthy subjects (HS), keratoconus (KC) patients and patients that underwent myopic photorefractive keratectomy (REF), using Goldmann applanation tonometry (GAT), dynamic contour tonometry (DCT), ocular response analyzer (ORA) and Corvis ST (CST). METHODS The study included 76(More)
PURPOSE The aim of this study is to describe the management of cataract and refractory glaucoma in a case of congenital aniridia (AN)-1. METHODS In an 18-year-old female patient affected by congenital AN, bilateral coloboma of the zonula and lens, cataract and glaucoma, pars plana vitrectomy, cataract extraction and subsequent transcorneal ciliary body(More)
The influence of timolol on aqueous humour production has been well documented, nevertheless it is unknown the real mechanism by which timolol produces this process. We have conceived the hypothesis that any alteration of natrium and kalium content following topical treatment of timolol was the main cause of the lowering rate of aqueous humour production.(More)