Mario A. Fichera

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BACKGROUND Parkinson's disease (PD) is characterized by various changes in motor excitability. OBJECTIVE To examine through Transcranial Magnetic Stimulation (TMS) cortical excitability, specifically addressing interhemispheric connections in PD. METHODS Nineteen PD patients with a predominant involvement of the left hemibody (7 females, age 61.7(More)
BACKGROUND Repetitive transcranial magnetic stimulation (rTMS) has been proposed as a potential treatment for Parkinson's disease (PD). H-coils, inducing deeper and wider magnetic fields compared to traditional coils, may be potentially useful in PD, characterized by widespread, bilateral involvement of cortico-subcortical circuits. OBJECTIVE To evaluate(More)
Among postural abnormalities in Parkinson’s disease (PD), striatal hand (SH) is a particularly underexplored phenomenon. It leads to extreme abnormalities of hand posture, causing altered dexterity, pain and disfigurement. In our study, three blinded investigators examined several pictures of the hands of individuals with PD (N = 40) and controls (N = 15).(More)
In the last few years, several dementia conditions have been recognized as responsible for speech disorders [1]. The underlying pathology is variable and encompasses Alzheimer’s disease (AD) [2] and frontotemporal lobar degeneration, including its variants such as corticobasal degeneration and progressive supranuclear palsy (PSP) [3]. Particularly, beside(More)
Japanese encephalitis (JE) represents a major health problem in Southeast Asia where it remains the most important cause of viral encephalitis. Rare in the developed countries, JE is caused by a mosquito-born flavi virus able to procure an extensive damage to the basal ganglia, which is accompanied by a very high mortality in the acute phase [1, 2]. In(More)
A 44-year-old male affected by mesenchymoma of the mediastinum was treated surgically. The neoplasm, localized in the postero-inferior mediastinum with prevalent development to the left, was found to consist of adipose, leiomuscular and myxoid tissue. The patient was asymptomatic. Complete removal of the neoplasm proved possible, and one year after surgery(More)