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Early detection of colorectal cancer (CRC) is currently based on fecal occult blood testing (FOBT) and colonoscopy, both which can significantly reduce CRC-related mortality. However, FOBT has low-sensitivity and specificity, whereas colonoscopy is labor- and cost-intensive. Therefore, the discovery of novel biomarkers that can be used for improved CRC(More)
The transition from normal epithelium to adenoma and, to invasive carcinoma in the human colon is associated with acquired molecular events taking 5-10 years for malignant transformation. We discovered CCAT1, a non-coding RNA over-expressed in colon cancer (CC), but not in normal tissues, thereby making it a potential disease-specific biomarker. We aimed to(More)
BACKGROUND Although thyroid nodules are common and diagnosed in over 5% of the adult population, only 5% harbor malignancy. Patients with clinically suspicious thyroid nodules need to undergo fine-needle aspiration biopsy (FNAB). The main limitation of FNAB remains indeterminate cytopathology. Only 20%-30% of the indeterminate nodules harbor malignancy, and(More)
Bilal Alaiyan (Bilal@hadassah.org.il) Nadia Elyayev (nadia.ilyayev@mail.huji.ac.il) Honguang Pan (hongguangp@hotmail.com) Mina Izadjoo (mjizadjoo@yahoo.com) Marina Roistacher (marinar24970@gmail.com) Vera Pavlov (verap210@gmail.com) Victoria Tzivin (vika.tsivin@gmail.com) David Halle (halledavid57@gmail.com) Alexander Stojadinovic(More)
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