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Valine Influences Production and Complex Composition of Glycopeptide Antibiotic A40926 in Fermentations of Nonomuraea sp. ATCC 39727.
Novel tetrapeptide inhibitors of bacterial protein synthesis produced by a Streptomyces sp.
In the course of a microbial product screening aimed at the discovery of novel antibiotics acting on bacterial protein synthesis, a complex of three structurally related tetrapeptides, namely,… Expand
A novel lantibiotic acting on bacterial cell wall synthesis produced by the uncommon actinomycete Planomonospora sp.
Important classes of antibiotics acting on bacterial cell wall biosynthesis, such as beta-lactams and glycopeptides, are used extensively in therapy and are now faced with a challenge because of the… Expand
Antiretrovirals: Simultaneous Determination of Five Protease Inhibitors and Three Nonnucleoside Transcriptase Inhibitors in Human Plasma by a Rapid High-Performance Liquid Chromatography–Mass…
- P. Villani, M. Feroggio, +4 authors M. Regazzi
- Chemistry, Medicine
- Therapeutic drug monitoring
- 1 August 2001
An analytical technique using liquid chromatography (LC) coupled with electrospray–mass spectrometry (ESI–MS) has been developed for the simultaneous determination of five protease inhibitors (PIs):… Expand
A derivative of the glycopeptide A40926 produced by inactivation of the beta-hydroxylase gene in Nonomuraea sp. ATCC39727.
The actinomycete Nonomuraea sp. ATCC39727 produces the glycopeptide A40926. In the corresponding dbv cluster, ORF28 encodes a putative hydroxylase. A gene replacement mutant of ORF28 in Nonomuraea… Expand
Valine influences production and complex composition of glycopeptide antibiotic A40926 in fermentations of Nonomuraea sp. ATCC 39727.
- Fabrizio Beltrametti, S. Jovetic, M. Feroggio, L. Gastaldo, E. Selva, F. Marinelli
- Medicine, Biology
- The Journal of antibiotics
- 25 January 2004
In actinomycetes the catabolism products of branched chain amino acids provide biosynthetic precursors for the formation of several lipid-containing antibiotics. We have determined in Nonomuraea sp.… Expand
Factors influencing cell fatty acid composition and A40926 antibiotic complex production in Nonomuraea sp. ATCC 39727
- S. Jovetic, M. Feroggio, F. Marinelli, G. Lancini
- Medicine, Biology
- Journal of Industrial Microbiology…
- 24 July 2008
A40926 is a glycopeptide antibiotic complex consisting of several structurally related factors. It is produced by fermentation of Nonomuraea sp. ATCC 39727 and the complex components differ in the… Expand
LC-MS Method for the Quantitation of Two Monoclonal Antibodies byMultiple Signature Peptides in Monkey Serum
- Rita Mastroianni, Marina Feroggio, Barbara Marsiglia, Clarissa Porzio Vernino, Simona Riva, Luca Barbero
- 2 July 2015
Evaluation of the in-vivo concentration of monoclonal antibody (mAb) mixtures is a challenging task. Here we report the application of an LC-MS bioanalytical method to quantify in monkey serum the… Expand