Marilyn Baird Mets

Learn More
Adult albinos and human infants share a number of common visual characteristics: both have low grating acuity, both lack a foveal pit (foveal hypoplasia), and both have much lower central cone densities than in the normal adult. We have explored the consequences of these characteristics by measuring both spatial and temporal contrast sensitivity in the(More)
The goal of this study was to determine the frequency of ophthalmic disorders in a group of young children with Down syndrome who were unselected for ophthalmic abnormalities, and to determine whether examination by a pediatric ophthalmologist should become standard practice. Of 77 children referred to a Down syndrome clinic at a teaching hospital and(More)
Previous experiments testing grating and vernier acuities in albino central vision are consistent with the hypothesis that the deficit in their monocular spatial processing is mainly due to the increased spacing of their foveal cones. This was tested by measuring albino spatial frequency discrimination over the range 0.25-4.0 cpd. The same experiments were(More)
A masking paradigm was used to measure the spatial frequency and orientation tuning of spatial mechanisms in the albino visual system. Threshold elevation curves obtained in this manner at test spatial frequencies of 0.25 cycles/deg (cpd), 0.50 cpd, and 1 cpd have the same shape as curves obtained from normal subjects at test frequencies two octaves higher.(More)
OBJECTIVES The purpose of this work was to determine whether visual impairment caused by toxoplasmic chorioretinitis is associated with impaired performance of specific tasks on standardized tests of cognitive function. If so, then we worked to determine whether there are patterns in these difficulties that provide a logical basis for development of(More)
OBJECTIVE To determine the incidence of new chorioretinal lesions in patients with congenital toxoplasmosis who were treated throughout their first year of life. DESIGN Prospective longitudinal observation of a cohort. PARTICIPANTS One hundred thirty-two children were studied as part of the longitudinal observation. METHODS One hundred thirty-two(More)
Intrauterine infections are important causes of childhood blindness in both developed and developing countries. Chorioretinal scars are the most characteristic eye manifestation of a congenital or prenatal infection. The various ocular manifestations of congenital infections, summarized by the mnemonic TORCH, and recent additions to the "other" category(More)
Retinoblastoma is the most common intraocular tumor in children. Current management includes broad-based treatments such as chemotherapy, enucleation, laser therapy, or cryotherapy. However, therapies that target specific pathways important for retinoblastoma progression could provide valuable alternatives for treatment. MicroRNAs are short, noncoding RNA(More)
Light-adapted and dark-adapted electroretinograms were obtained in 27 premature infants who were screened for retinopathy of prematurity shortly after birth. Thirteen showed no retinopathy and 13 had mild to moderate retinopathy, which ranged from stage I, zone III (International Classification) to stage III, zone II. Measurements were made during the first(More)
IMPORTANCE Children with a history of amblyopia, even if resolved, exhibit impaired visual-auditory integration and perceive speech differently. OBJECTIVE To determine whether a history of amblyopia is associated with abnormal visual-auditory speech integration. DESIGN, SETTING, AND PARTICIPANTS Retrospective observational study at an academic pediatric(More)