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Unlike the aphasic syndromes, the organization of affective prosody in brain has remained controversial because affective-prosodic deficits may occur after left or right brain damage. However, different patterns of deficits are observed following left and right brain damage that suggest affective prosody is a dominant and lateralized function of the right(More)
BACKGROUND Affective prosody is a nonlinguistic aspect of language that conveys emotion and attitude during discourse. It is a dominant function of the right hemisphere. Because skills associated with the right hemisphere have been found to be impaired in alcoholics, this study explored the possibility that affective prosodic functioning may be sensitive to(More)
Most clinical research has focused on intensity differences of facial expressions between the right and left hemiface to explore lateralization of emotions in the brain. Observations by social psychologists, however, suggest that control of facial expression is organized predominantly across the upper-lower facial axis because of the phenomena of facial(More)
Subjective human judgments of emotion in speech have been considered to be less reliable than acoustic analyses in scientific studies, but acoustic analyses have had limited ability to detect subtle vocal nuances that give useful social information about human intent and meaning to discourse partners. Two post hoc analyses were undertaken to determine if(More)
Affective prosody is a nonlinguistic aspect of language that conveys emotions and attitudes during discourse. In this study the neurological basis of affective prosodic comprehension (APC) dysfunction in alcoholics (ALC) and fetal alcohol-exposed adults (FAexp) was explored. Subjects were previously tested for APC by use of the Aprosodia Battery, including(More)
The relationship between a biological process and a behavioral trait indicates a proximate mechanism by which natural selection can act. In that context, examining an aspect of infant health is one method of investigating the adaptive significance of infant-directed speech (ID speech), and it could help to explain the widespread use of this communication(More)
The Aprosodia Battery was developed to distinguish different patterns of affective-prosodic deficits in patients with left versus right brain damage by using affective utterances with incrementally reduced verbal-articulatory demands. It has also been used to assess affective-prosodic performance in various clinical groups, including patients with(More)
OBJECTIVE Leukoaraiosis (LA) is a common finding on MRI scans of the elderly. However, its exact relationship to cognitive decline and dementia is in dispute. Because LA involves the paracallosal white matter, we sought to determine if LA, uncomplicated by ischemic lesions or complaints of cognitive impairment, is associated with cognitive loss or(More)
1H- and 31P-NMR and UV-absorption studies were carried out with the oligonucleotide strands d(AGCT-TATC-ATC-GATAAGCT) (-ATC-) and d(AGCTTATC-GAT-GATAAGCT) (-GAT-) contained in the strongest and salt resistant cleavage site for topoisomerase II in pBR322 DNA. We found that the two oligonucleotides were stabilized under a hairpin structure characterized by a(More)