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PURPOSE To investigate the role played by docosahexaenoic acid (DHA) in the retina, and more specifically, its ability to protect the retina from kainic acid (KA)-induced retinal damage. METHODS Three-week-old female Wistar rats were used. DHA (1000 mg/kg per day) was fed to the rats for 7, 14, and 28 days, and the concentrations of DHA and arachidonic(More)
PURPOSE To study the interaction of visual signals from both eyes with visual evoked cortical potentials (VECPs) elicited by pseudorandom binary sequence (PRBS) stimuli. METHODS A PRBS was used to drive two independent LED arrays to elicit VECPs. The right and left eyes were simultaneously stimulated by two different series of PRBS stimuli. The impulse(More)
The neuroprotective effect of MCI-9042 (Mitsubishi Pharma Corporation) was investigated on glutamate-induced retinal ganglion cell (RGC) death in vitro and on rat retinal ischemia in vivo. RGCs were purified from retinal cells isolated from 6-day-old Wistar rats and cultured in serum-free media. After application of 25 microM glutamate, the viability of(More)
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