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BACKGROUND Formation of antibodies to infliximab (ATI) inversely correlates with functional drug levels and clinical outcome. Comparison of drug levels and anti-drug antibody monitoring is hampered by lack of standardisation. AIM To determine the correlation between three different assays for measuring infliximab and ATI. METHODS Serum samples and(More)
BACKGROUND Only a few international studies have assessed the economic burden of atopic dermatitis (AD), and no costs-of-illness study for AD has been done for the Netherlands. OBJECTIVES To estimate the incidence, prevalence and health-care costs of AD in the Netherlands and to put these in an international perspective. METHODS We conducted a(More)
  • A. Ceci, M. Felisi, +7 authors I. Wong
  • 2006
The 1995–2005 balance of EMEA activities in the field of paediatric medicines was evaluated, taking into account the number both of drugs authorised for children and paediatric studies supporting the Marketing Authorisation (MA). Data on drugs authorised by EMEA were extracted from EPARs (European Public Assessment Reports). Active substance, year of(More)
OBJECTIVE The purpose of this study was to assess (patient) characteristics that might influence the prevalence of physiological uptake of [18F]fluorodeoxyglucose (FDG) in the neck and upper chest region (FDG NUC) in positron emission tomography (PET) imaging. METHODS Retrospective study of static FDG PET scans in patients with malignant lymphoma, head(More)
BACKGROUND The purpose of this prospective study was to evaluate the clinical diagnostic value of iodine-124 (124I)-positron emission tomography (PET) in patients with advanced differentiated thyroid carcinoma (DTC) and to compare the 124I-PET imaging results with the 131I whole-body scan (WBS). MATERIALS AND METHODS Twenty patients with histologically(More)
OBJECTIVE A distinctive pattern of physiological symmetrical uptake of 18F-fluorodeoxyglucose (18F-FDG) in the neck and upper chest region is a phenomenon that is sometimes observed on positron emission tomography (PET) scans of some oncologic patients. Initially, it was assumed to be muscle uptake secondary to patient anxiety or tension, which could be(More)
UNLABELLED Since the introduction of the bivalent human papilloma virus (HPV) vaccine in the Netherlands, migraine has been reported as a notable event in the passive safety surveillance system. Research on the association between HPV vaccination and migraine is needed. Therefore, potential migraine cases in 2008-2010 were selected from a group of general(More)
  • M. van Riemsdijk, J. Ditters, +4 authors B. Stricker
  • 2002
Abstract Introduction. It has been suggested that neuropsychiatric events during use of mefloquine are more common in females than in males and are partly explained by the psychological stress of travelling. Therefore, we investigated neuropsychiatric events in females and males on mefloquine in the 3-week prophylactic period that precedes travelling.(More)
Normal metallothionein [(MT)+/+] and MT-null (MT-/-) mice were used to examine the influence of MT on Zn retention and the metabolic consequences of 2 d food deprivation, with and without inflammation induced by intraperitoneal injection of bacterial endotoxin lipopolysaccharide (LPS). LPS reduced fecal Zn concentration in MT+/+ mice from 5.9 +/- 0.2(More)