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  • Alexander Espinosa, Janosch Hennig, +7 authors Marie Wahren-Herlenius
  • Biology, Medicine
  • The Journal of biological chemistry
  • 2011 (First Publication: 23 August 2011)
  • Ro52 (TRIM21) is an E3 ligase of the tripartite motif family that negatively regulates proinflammatory cytokine production by ubiquitinating transcription factors of the interferon regulatory factorContinue Reading
  • Lars Ottosson, Janosch Hennig, Alexander Espinosa, Susanna Brauner, Marie Wahren-Herlenius, Maria Sunnerhagen
  • Biology, Medicine
  • Molecular immunology
  • 2006 (First Publication: 1 February 2006)
  • Ro52, one of the major autoantigens in the rheumatic disease Sjögren's syndrome (SS), belongs to the tripartite motif (TRIM) or RING-B-box-coiled-coil (RBCC) protein family, thus comprising anContinue Reading
  • E Welin Henriksson, Marie Wahren-Herlenius, Ingvar Lundberg, Erik C. Mellquist, Ingvar Pettersson
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 1999 (First Publication: 7 December 1999)
  • Epitopes depending on three-dimensional folding of proteins have during recent years been acknowledged to be main targets for many autoantibodies. However, a detailed resolution ofContinue Reading
  • Janosch Hennig, Lars Ottosson, +5 authors Maria Sunnerhagen
  • Biology, Medicine
  • The Journal of biological chemistry
  • 2005 (First Publication: 30 September 2005)
  • Ro52 is one of the major autoantigens targeted in the autoimmune disease Sjögren syndrome. By sequence similarity, Ro52 belongs to the RING-B-box-coiled-coil (RBCC) protein family. Disease-relatedContinue Reading
  • Janosch Hennig, Anders Bresell, +4 authors Maria Sunnerhagen
  • Chemistry, Medicine
  • Journal of molecular biology
  • 2008 (First Publication: 1 March 2008)
  • Ro52 is a major autoantigen that is targeted in the autoimmune disease Sjögren syndrome and belongs to the tripartite motif (TRIM) protein family. Disease-related antigenic epitopes are mainly foundContinue Reading
  • Stina Salomonsson, Lars Ottosson, +5 authors Marie Wahren-Herlenius
  • Biology, Medicine
  • Journal of autoimmunity
  • 2004 (First Publication: 1 March 2004)
  • Autoantibodies against amino acid 200-239 (p200) in the predicted leucine zipper region of the Ro52 protein are associated with congenital heart block, a potentially fatal condition that may affectContinue Reading