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A nuclease hypersensitive element in the human c-myc promoter adopts several distinct i-tetraplex structures.
Nucleic acid structure-function correlations are pivotal to major biological events like transcription, replication, and recombination. Depending on intracellular conditions in vivo and bufferExpand
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In vitro anti-inflammatory activity of carvacrol: Inhibitory effect on COX-2 catalyzed prostaglandin E2 biosynthesisb
Possible anti-inflammatory effect of carvacrol was evaluated by in vitro cyclooxygenase-2 (COX-2) assay. Carvacrol inhibited production of prostaglandin E2 catalysed by COX-2 with an IC50 value ofExpand
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Impact of Wines and Wine Constituents on Cyclooxygenase-1, Cyclooxygenase-2, and 5-Lipoxygenase Catalytic Activity
Cyclooxygenases and lipoxygenases are proinflammatory enzymes; the former affects platelet aggregation, vasoconstriction, vasodilatation and later the development of atherosclerosis. Red wines fromExpand
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[Chlamydia trachomatis in men with impaired fertility].
OBJECTIVE The objective of the prospective study was to assess whether there exists a relationship between the results of positive laboratory tests for the presence of Chlamydia infection (assessmentExpand
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Inhibition of In Vitro Leukotriene B4 Biosynthesis in Human Neutrophil Granulocytes and Docking Studies of Natural Quinones
Quinones are compounds frequently contained in medicinal plants used for the treatment of inflammatory diseases. Therefore, the impact of plant-derived quinones on the arachidonic acid metabolicExpand
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Redox and non-redox mechanism of in vitro cyclooxygenase inhibition by natural quinones.
In this study, ten anthra-, nine naphtho-, and five benzoquinone compounds of natural origin and five synthetic naphthoquinones were assessed, using an enzymatic in vitro assay, for their potentialExpand
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Determination of Oxygen Radical Absorbance Capacity of Black Cumin (Nigella sativa) Seed Quinone Compounds
In this study, the antioxidant capacities of main quinone constituents of Nigella sativa seeds, namely dithymoquinone (1), thymohydroquinone (2) and thymoquinone (3), were compared using DPPH andExpand
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Synthesis of alkylcarbonate analogs of O-acetyl-ADP-ribose.
The non-hydrolyzable alkylcarbonate analogs of O-acetyl-ADP-ribose have been synthesized from the phosphorylated ribose derivatives after coupling with AMP morpholidate promoted by mechanicalExpand
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Paclitaxel conjugation with the analog of the gonadotropin-releasing hormone as a targeting moiety.
A new targeted conjugates in which paclitaxel was used as a cytostatic compound and an analog of the gonadotropin-releasing hormone (GnRH) as a targeting moiety were synthesized. The molecule of theExpand
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Alkyloxycarbonyl group migration in furanosides
Abstract A migration of methyloxycarbonyl group from secondary to primary hydroxyl was observed in furanosides (ribosides and xylosides) under usual desilylation conditions using tetrabutylammoniumExpand
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