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AIM To assess the effects of iron removal on cytochrome P450 2E1 activity and oxidative stress in dysmetabolic iron overload syndrome. METHODS Forty-eight patients were randomized to phlebotomy therapy consisting of removal of 300-500 mL of blood every 14 days until serum ferritin levels dropped under 100 microg/L or to follow-up without phlebotomy(More)
BACKGROUND The potential use of cystatin C has recently emerged to evaluate kidney function following transplantation. Analytical performance of a particle-enhanced turbidimetric immunoassay (PETIA) using Dako Cytomation Cystatin C reagents on an Olympus AU640(®) analyzer was evaluated. Clinical relevance was determined by comparison with a reference method(More)
BACKGROUND To evaluate the contamination of delivery systems after an aerosol therapy session in patients with cystic fibrosis who have chronic Pseudomonas aeruginosa infection. METHODS Fifty-three patients with cystic fibrosis were enrolled in the study from March 1996 to June 1997. All patients were age 7 years or older and had P aeruginosa infection.(More)
This retrospective study was conducted on 144 lower extremities (133 patients) with deep venous reflux treated with surgery to restore venous valvular function. Clinically, 51% of patients were in class C5-C6, and based on etiology, patients were equally divided into primary and secondary venous disease. Four surgical procedures were used: valvuloplasty(More)
BNP and NT-proBNP are both well established as diagnostic and prognostic markers for congestive heart failure (CHF). However it remains for the biologist to choose between these two biomarkers depending on his equipment availability. The aim of this study was to compare results obtained with the Biosite Triage BNP assay and the Dade Behring NT-proBNP assay(More)
The surgical treatment of chronic venous insufficiency in the lower limbs, whether it is a case of so-called 'essential' varices or of post-phlebitic disorders, presents a certain number of risks of venous thrombosis and especially of cutaneous necrosis or of cicatricial detachment in operations of the Lindon or Felder type. Given a less significant(More)
The observations concern ischemic accidents with various localizations (lower limbs, tongue, uterus, intestine, heart, liver) corresponding to 4 observations for which ergot derivatives (ergotamine tartrate) can be responsible. The most typical accidents are localized at the level of limbs and especially of lower limbs. In the greatest part of observations,(More)
  • M Perrin
  • 1994
Non invasive explorations of chronic venous disease, particularly echo-doppler techniques, have greatly improved our understanding of the underlying pathophysiological mechanisms. The findings of the physical examination are however still the basis of all indications for surgery. The most frequently performed procedures involve treatment of superficial(More)