Marie-Noëlle Horcajada

Learn More
Step-reduction (SR) in older adults results in muscle atrophy and an attenuated rise in postprandial muscle protein synthesis (MPS): anabolic resistance. Knowing that resistance exercise (RT) can enhance MPS, we examined whether RT could enhance MPS following 2 weeks of SR. In addition, as we postulated that SR may impair feeding-induced vasodilation(More)
AIM The aim of this work was to evaluate the effects of carnosol, a rosemary polyphenol, on pro-inflammatory and catabolic mediators of cartilage breakdown in chondrocytes and via bone-cartilage crosstalk. MATERIALS AND METHODS Osteoarthritic (OA) human chondrocytes were cultured in alginate beads for 4 days in presence or absence of carnosol (6 nM to 9(More)
Animal models of metabolic acidosis are generally based on drastic treatments and are poorly suitable as models of latent metabolic acidosis (LMA). Specific rodent diets have been evaluated as LMA models, together with their responsiveness to dietary alkalinizing factors. Using this model, the possibility to obtain LMA states with moderate levels of protein(More)
  • 1