Marie Germaine Higgins

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The combination of phenobarbital (PB) and phenytoin (PHT) was recommended for many years for treatment of epilepsy in humans. We tested the effectiveness of the combination in a model of hippocampal seizures termed maximal dentate activation (MDA). Two parameters of MDA were measured: duration and time to onset. Neither the vehicle controls nor PHT 80 mg/kg(More)
The motions of comets and neutron stars have been integrated over five billion years in the Galactic potential to determine a gamma-ray burst distribution, presuming that bursts are the result of interactions between these two families of objects. The comets originate in two distinct populations one from ejection by stars in the Galactic disk, and the other(More)
Two types of afterdischarges have been recorded in the dentate gyrus after trains of electrical stimulation. The first afterdischarge contains predominantly broad positive potentials. The second afterdischarge contains bursts of large amplitude population spikes and has been termed maximal dentate activation. It has been proposed that the first(More)
The purpose of this longitudinal, descriptive study was to compare new graduate self-appraisals of nursing performance with those of their evaluators and provide information about the length of time new graduates practiced before they and their evaluators agreed about their level of performance. The panel of new graduates and their evaluators were surveyed(More)
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