Marie Dupuch

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Pharmacovigilance is the activity related to the collection, analysis and prevention of adverse drug reactions (ADRs) induced by drugs or biologics. The detection of adverse drug reactions is performed thanks to statistical algorithms and to groupings of ADR terms. Standardized MedDRA Queries (SMQs) are the groupings which become a standard for assisting(More)
Because of the ever-increasing amount of information in patients' EHRs, healthcare professionals may face difficulties for making diagnoses and/or therapeutic decisions. Moreover, patients may misunderstand their health status. These medical practitioners need effective tools to locate in real time relevant elements within the patients' EHR and visualize(More)
We present a novel method for adaptation of existing terminologies. Within biomedical domain and when no textual corpora for building terminologies are available, we exploit UMLS metathesaurus which merges over a hundred existing biomedical terminologies and on-tologies. We exploit also algorithms for measuring the semantic similarity in order to limit,(More)
The identification of semantically similar linguistic expressions despite their formal difference is an important task within NLP applications (information retrieval and extraction, terminology structuring...) We propose to detect the semantic relatedness between biomed-ical terms from the pharmacovigilance area. Two approaches are exploited: semantic(More)
Pharmacovigilance is the activity related to the collection, analysis and prevention of adverse drug reactions (ADRs) induced by drugs or biologics. Besides other methods, statistical algorithms are used to detect previously unknown ADRs, and it was noted that groupings of ADR terms can further improve safety signal detection. Standardised MedDRA Queries(More)
BACKGROUND Pharmacovigilance is the activity related to the collection, analysis and prevention of adverse drug reactions (ADRs) induced by drugs or biologics. The detection of adverse drug reactions is performed using statistical algorithms and groupings of ADR terms from the MedDRA (Medical Dictionary for Drug Regulatory Activities) terminology.(More)
Pharmacovigilance is the activity related to the collection, analysis and prevention of adverse drug reactions (ADRs) induced by drugs. This activity is usually performed within dedicated databases (national, European, international...), in which the ADRs declared for patients are usually coded with a specific controlled terminology MedDRA (Medical(More)
In different applications (i.e., information retrieval, filtering or analysis), it is useful to detect similar terms and to provide the possibility to use them jointly. Clustering of terms is one of the methods which can be exploited for this. In our study, we propose to test three methods dedicated to the clustering of terms (hierarchical ascendant(More)
RÉSUMÉ Nous proposons d'exploiter des méthodes du Traitement Automatique de Langues dédiées à la structuration de terminologie indépendamment dans deux langues (anglais et français) et de fusionner ensuite les résultats obtenus dans chaque langue. Les termes sont groupés en clusters grâce aux relations générées. L'évaluation de ces relations est effectuée(More)