Marie Dupuch

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Because of the ever-increasing amount of information in patients' EHRs, healthcare professionals may face difficulties for making diagnoses and/or therapeutic decisions. Moreover, patients may misunderstand their health status. These medical practitioners need effective tools to locate in real time relevant elements within the patients' EHR and visualize(More)
Pharmacovigilance is the activity related to the collection, analysis and prevention of adverse drug reactions (ADRs) induced by drugs or biologics. The detection of adverse drug reactions is performed thanks to statistical algorithms and to groupings of ADR terms. Standardized MedDRA Queries (SMQs) are the groupings which become a standard for assisting(More)
We present a novel method for adaptation of existing terminologies. Within biomedical domain and when no textual corpora for building terminologies are available, we exploit UMLS metathesaurus which merges over a hundred existing biomedical terminologies and ontologies. We exploit also algorithms for measuring the semantic similarity in order to limit,(More)
The identification of semantically similar linguistic expressions despite their formal difference is an important task within NLP applications (information retrieval and extraction, terminology structuring...) We propose to detect the semantic relatedness between biomedical terms from the pharmacovigilance area. Two approaches are exploited: semantic(More)
Pharmacovigilance is the activity related to the collection, analysis and prevention of adverse drug reactions (ADRs) induced by drugs. It leads to the safety survey of pharmaceutical products. The pharmacovigilance process benefits from the traditional statistical approaches and also from the qualitative information on semantic relations between close ADR(More)
Pharmacovigilance is the activity related to the collection, analysis and prevention of adverse drug reactions (ADRs) induced by drugs. This activity is usually performed within dedicated databases (national, European, international...), in which the ADRs declared for patients are usually coded with a specific controlled terminology MedDRA (Medical(More)
The surveillance of the adverse drug reaction profile and the prevention of the potential or known risk related to the use of medicine products is a core activity of pharmacovigilance. Signal detection and monitoring of identified risks benefit from traditional statistical approaches and also from qualitative information on semantic relations between close(More)
Pharmacovigilance is the activity related to the collection, analysis and prevention of adverse drug reactions (ADRs) induced by drugs or biologics. Besides other methods, statistical algorithms are used to detect previously unknown ADRs, and it was noted that groupings of ADR terms can further improve safety signal detection. Standardised MedDRA Queries(More)