Marie-Christine Legrand

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During the last decade, growing efforts have focused on human papillomavirus (HPV) detection using liquid hybridization, conventional PCR, and real-time PCR-based methods to increase the overall proportion of patients participating in cervical cancer screening procedures. We proposed a new general HPV DNA real-time PCR on the Mx4000 (Stratagene) and(More)
A novel human Coronavirus (HCoV) was this year recognized as the etiological agent of the Severe Acute Respiratory Syndrome. Two other HCoV (HCoV-229E and HCoV-OC43) have been known for 30 years. HCoV-229E has been recently involved in nosocomial respiratory viral infections in high-risk children. However, their diagnosis is not routinely performed.(More)
In autumn 2000 and 2001, four young immunocompetent children were admitted to our paediatric emergency ward for vesicular stomatitis, typical of primary herpes virus infection, and subsequently found to have a coxsackie A16-like virus. None of them had hand-foot-andmouth disease nor herpangina. Primary herpetic gingivostomatitis, herpangina or aphthous(More)
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