Marie-Annick Porcher

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The first objective of this study was to confirm that 4 days of head-down tilt (HDT) were sufficient to induce orthostatic intolerance, and to check if 4 days of physical confinement may also induce orthostatic intolerance. Evidence of orthostatic intolerance during tilt-up tests was obtained from blood pressure and clinical criteria. The second objective(More)
The objectives were to evaluate cardiac and peripheral changes induced by microgravity with and without countermeasures (CM), to assess the peripheral response to orthostatic tests (tilt, LBNP). Inflight or HDT, we used echography and Doppler to assess the left heart function and the peripheral arteries. We studied the cardiovascular system during 1) 21-d(More)
The scientific objectives was to quantify the vascular changes in the brain, eye fundus, renal parenchyma, and splanchnic network. Heart, portal, jugular, femoral veins were investigate by Echography. The cerebral mesenteric, renal and ophthalmic arteries were investigated by Doppler. Eye fundus vein an papilla were investigated by optical video eye fundus.(More)
UNLABELLED The objective was to design and validate a method for tele-operating (from an expert site) an echographic examination in an isolated site. METHOD The isolated places, defined as areas with reduced medical facilities, could be secondary hospitals 20 to 50 km from the university hospital, or dispensaries in Africa or Amazonia, or a moving(More)
Ultrasound Doppler imaging and electrocardiography were used to study hemodynamic responses to spaceflight onboard the Mir space station. Cardiovascular adaptation was studied at rest and during the use of thigh cuffs or "Bracelets" for weightlessness countermeasures. Specific changes in hemodynamic parameters are presented and discussed, along with an(More)
Lower body negative pressure (LBNP) was used during the Mir spaceflight in a study of orthostatic tolerance. Hemodynamic responses were measured including heart rate, blood pressure, cerebral artery blood flow, and lower limb vascular resistance. Results showed that femoral flow volume decreased, which may be due to hypovolemia and reduced cardiac output.(More)
As human will stay for long duration in isolated sites like ISS there will be a need to perform quick and reliable diagnosis to evaluate the gravity of the pathology in presence of clinical symptoms. Many pathological situations (abnormal heart rate, pericardic collection, mitral prolaps, cholecystis, renal lithiasis, normal and ectopic pregnancies, ovarian(More)
OBJECTIVE Compare various Doppler methods for the quantification of the degree of stenosis on 85 patients. METHOD the following parameters were measured: maximal velocity (Vmax) inside the stenosis (PW), grades of spectral disturbances at the outlet of the stenosis (PW-CW), index of spectral disturbance (STI) at the outlet of the stenosis (PW-CW), ratio(More)
OBJECTIVE the aim of this work was to quantify the intensity of the vasodilation induced by dipyridamole used to simulate a stress test during a myocardial tomoscintigraphy. METHODS Doppler measurements of the femoral artery and the thoracic aorta were made on 26 patients (11 men, 15 women), using transducers attached to the skin, measurements being(More)
OBJECTIVE The objectives of this preliminary work were to evaluate the distribution of an ultrasound contrast agent (UCA) (microbubbles) in different arterial regions (brain, kidney, lower limbs) using the Doppler spectrum brightness analysis and to discuss the results in the context of decompression physiology. METHOD There were four patients who(More)