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CONTEXT Emotion regulation deficits figure prominently in generalized anxiety disorder (GAD) and in other anxiety and mood disorders. Research examining emotion regulation and top-down modulation has implicated reduced coupling of the amygdala with prefrontal cortex and anterior cingulate cortex, suggesting altered frontolimbic white matter connectivity in(More)
The dramatic phenotypic changes that occur in organisms during domestication leave indelible imprints on their genomes. Although many domesticated plants and animals have been systematically compared with their wild genetic stocks, the molecular and genomic processes underlying fungal domestication have received less attention. Here, we present a nearly(More)
Although the idea that entropy alone is suucient to produce an ordered state is an old one in colloidal science 11, the notion remains counter-intuitive and it is often assumed that attractive i n teractions are necessary to generate phases with long-range order. The phase behaviour for both rods and spheres has been studied experimentally 1, 5, 6, 7, 8, 9,(More)
Infectious diseases are increasingly recognized as an important force driving population dynamics, conservation biology, and natural selection in wildlife populations. Infectious agents have been implicated in the decline of small or endangered populations and may act to constrain population size, distribution, growth rates, or migration patterns. Further,(More)
PURPOSE Little is known about the role of sequence variation in the pathology of HSV-1 keratitis virus. The goal was to show that a multiplex, high-throughput genome-sequencing approach is feasible for simultaneously sequencing seven HSV-1 ocular strains. METHODS A genome sequencer was used to sequence the HSV-1 ocular isolates TFT401, 134, CJ311, CJ360,(More)
We present an experimental study of the isotropic-nematic phase transition in an aqueous mixture of charged semiflexible rods ( fd virus) and neutral polymer (Dextran). A complete phase diagram is measured as a function of ionic strength and polymer molecular weight. At high ionic strength we find that adding polymer widens the isotropic-nematic coexistence(More)
Methionine is an important nutrient in animal feed and several approaches have been developed to increase methionine concentration in maize (Zea mays L.) grain. One approach is through traditional breeding using recurrent selection. Using divergent selection, genetically related populations with extreme differences in grain methionine content were produced.(More)
The dramatic phenotypic changes that occur in organisms during domestication leave indelible imprints on their genomes. Although many domesticated plants and animals have been systematically compared to their wild genetic stocks, the molecular and genomic processes underlying fungal domestication have received less attention. Here we present a nearly(More)
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