Mariano Pizzuti

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The objective of this study was to evaluate intravesical gemcitabine in high-risk nonmuscle-invasive bladder cancer (NMIBC) refractory to bacillus Calmette-Guérin (BCG). This was a prospective multicentre single-arm trial. Eligible patients were those with high-risk NMIBC refractory to BCG therapy, for which radical cystectomy was indicated but not(More)
UNLABELLED ESSENTIALS: The differential diagnosis among thrombotic microangiopathies (TMAs) is challenging. We studied a case of TMA with neurologic symptoms, no renal impairment and normal ADAMTS-13 levels. Two novel mutations in complement factor I and thrombomodulin genes were identified. Complement-regulator genes can be involved in TMAs with normal(More)
Grundlagen: Dringliche Operationen oder Notoperationen in der Herzchirurgie bei älteren Patienten sind durch hohe operative Mortalität und inakzeptabel postoperative Lebensqualität belastet. METHODIK: Zwischen 1998 und 2007 erhielten 251 Patienten über 80 Jahren eine dringliche (n = 229) oder Notoperation (n = 22). Um Risikofaktoren für den postoperative(More)
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