Mariana S A Souza

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BACKGROUND AND PURPOSE Neuropathological studies and one positron emission tomography study demonstrated involvement of the thalamus in Machado-Joseph disease (MJD), but a large series of patients has not been studied. Our objective was to perform an automated and a manual segmentation of the thalamus in patients with MJD. METHODS We used the MarsBar(More)
HTLV-1-associated myelopathy (HAM) is a classic neuro-logical disease, but cognitive impairment and altered signal intensity on MRI scans of the brain are described in the literature and suggest a more extensive neurological damage. This is a cross-sectional study, conducted between March 17 th and September 28 th , 2012 in the GIPH cohort, Brazil. HAM was(More)
Since 1997, the Interdisciplinary Research Group on HTLV-1/2 (GIPH) has been following individuals infected with HTLV in Minas Gerais, Brazil, in an open prospective cohort study. The HAM diagnosis is based on clinical parameters, with support of complementary exams to exclude other possible causes of myelopathy. The objective of this study was to evaluate(More)
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