Mariana Mărdărescu

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In the late 1980s an HIV-1 epidemic emerged in Romania that was dominated by subtype F1. The main route of infection is believed to be parenteral transmission in children. We sequenced partial pol coding regions of 70 subtype F1 samples from children and adolescents from the PENTA-EPPICC network of which 67 were from Romania. Phylogenetic reconstruction(More)
At present, women represent approximately one-third of new diagnoses of HIV in Europe - most are infected by heterosexual transmission. Some specific populations of women, such as migrants, sex workers and those who are intravenous drug users, may be at increased risk of HIV infection. Women living with HIV face a range of intersecting situations and(More)
BACKGROUND A significant increase in HIV-1 diagnoses was reported among Injecting Drug Users (IDUs) in the Athens (17-fold) and Bucharest (9-fold) metropolitan areas starting 2011. METHODS Molecular analyses were conducted on HIV-1 sequences from IDUs comprising 51% and 20% of the diagnosed cases among IDUs during 2011-2013 for Greece and Romania,(More)
Even though cardiac disease is not frequent in HIV infected children, it is associated with poor prognosis. Dilated cardiomyopathy is the most frequent heart disease associated with HIV infection. In HIV children the most frequent cardiac lesion is dysfunction and/or enlarged dimensions of the left ventricle. The pathogenesis is complex, the most important(More)
BACKGROUND The Romanian HIV epidemic is characterized by a high prevalence among children born in the late '80s, perinatally infected. The impact of long-term treatment on their offspring is unknown. We evaluated the influence of prenatal care on the rate of premature birth among the HIV-exposed children of heavily treated HIV-infected mothers in two(More)
OBJECTIVES (1) to evaluate the effect of HAART on CMV viraemia in co-infected patients, in the absence of specific anti-CMV therapy; (2) to compare 2 molecular biology techniques for the detection and quantification of CMV-DNA in these patients. METHODS We present the preliminary data of an ongoing prospective research grant on newly diagnosed HIV(More)
INTRODUCTION Late presentation is associated with increased healthcare costs, rates of HIV transmission and poor outcome. In Romania, in 2012, one third of individuals with new HIV diagnosis were late presenters (LP). OBJECTIVE The aim of the study was to evaluate the epidemiological and clinical characteristics associated with late presentation. (More)
Objective: to identify types of birth defects in HIV vertically exposed children and to determine the rate of congenital disorders counted in children born to HIV infected mothers. We analyzed the data recorded for HIV perinatally exposed children followed up in the National Institute for Infectious Diseases “Prof. Dr. Matei Balş”, Bucharest, the Pediatric(More)
A1 The outcome of patients with recurrent versus non-recurrent pneumococcal meningitis in a tertiary health-care hospital in Bucharest Cristian-Mihail Niculae, Eliza Manea, Raluca Jipa, Simona Merisor, Ruxandra Moroti, Serban Benea, Adriana Hristea National Institute for Infectious Diseases “Prof. Dr. Matei Balș”, Bucharest, Romania; Carol Davila University(More)