Mariana Crotti Franco

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This paper quantitatively defines the nanoscale topography of the basement membrane underlying the anterior corneal epithelium of the macaque. Excised corneal buttons from macaques were placed in 2.5 mM ethylenediaminetetraacetate (EDTA) for 2.5 h, after which the epithelium was carefully removed to expose the underlying basement membrane. The integrity of(More)
The effect of surface chemistry on the proliferation and adhesion of SV-40 human corneal epithelial cells was investigated. The surface chemistry of substrates was controlled by the deposition of self-assembled monolayers (SAMs) terminated with the following functional groups: -CF3, -CH3, -CO(2)H, and -NH(2). SAMs of alkanethiols on gold and of(More)
We described angiotensin-I-converting enzyme (ACE) isoforms with molecular masses of 190, 90, and 65 kDa in the urine of normotensive offspring of hypertensive subjects. Since they did not appear in equal amounts, we suggested that 90 kDa ACE might be a marker for hypertension. We evaluated the endothelial response in normotensive offspring with or without(More)
Evaluation of the state intervention project to improve quality of life and reduce the complications associated with aging: ''Add health to your years'' Objective: This paper evaluates the effectiveness of a Public Health program for the elderly based on health promotion and pathologies prevention, in order to avoid complications associated with illnesses(More)
Members of the genus Pilocarpus are the only natural source of the imidazole alkaloid pilocarpine, a plant metabolite widely used in the pharmaceutical industry. Although there is variation in the pilocarpine content in Pilocarpus, only the species Pilocarpus spicatus does not have pilocarpine, although it contains other imidazole alkaloids related with(More)
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