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  • André Lopes Carvalho, Carmen Jerónimo, +18 authors Joseph A. Califano
  • Medicine
  • Clinical Cancer Research
  • 2008 (First Publication: 1 January 2008)
  • Purpose: To evaluate aberrant promoter hypermethylation of candidate tumor suppressor genes as a means to detect epigenetic alterations specific to solid tumors, including head and neck squamous cellExpand
  • André Lopes Carvalho, Alice T Chuang, +19 authors Joseph A. Califano
  • Biology, Medicine
  • Cancer research
  • 2006 (First Publication: 1 October 2006)
  • Deleted in colorectal cancer (DCC) is a candidate tumor-suppressor gene located at chromosome 18q21. However, DCC gene was found to have few somatic mutations and the heterozygous mice (DCC(+/-))Expand
  • André Lopes Carvalho, Rui Henrique, +15 authors Joseph A. Califano
  • Biology, Medicine
  • Clinical Cancer Research
  • 2011 (First Publication: 31 May 2011)
  • Purpose: Hypermethylation of tumor suppressor gene promoters has been found in head and neck squamous carcinoma (HNSCC) and other solid tumors. We evaluated these alterations in pretreatment salivaryExpand