Mariana Bonetto

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BACKGROUND The prognosis of long-term severe disorders of consciousness due to traumatic brain injury is discouraging. There is little definitive evidence of the underlying mechanisms, but a deficiency of the dopaminergic system may be involved. METHODS In a prospective open-labelled clinical study, the feasibility, relative efficacy and safety of(More)
BACKGROUND Traumatic brain injury (TBI) can induce long-term severe disorders of consciousness. Evidence suggests an underlying dopaminergic deficit. Dopamine agonists may therefore play an important role in recovery of consciousness. OBJECTIVE To explore the response to continuous subcutaneous administration of apomorphine in a patient who had remained(More)
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