Mariana A.B. Rosales

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PURPOSE To investigate if nitric oxide (NO) system contributes to the beneficial effect of angiotensin II type 1 receptor (AT(1)) blocker losartan in the retina of diabetic spontaneously hypertensive(More)
PURPOSE The purpose of this study was to investigate the efficacy of tempol (4-hydroxy-2,2,6,6-tetramethylpiperidine-N-oxyl), a superoxide dismutase mimetic, in preventing early retinal molecular(More)
PURPOSE Diabetic retinopathy (DR) is associated with nitrosative stress. The purpose of this study was to evaluate the beneficial effects of S-nitrosoglutathione (GSNO) eye drop treatment on an(More)
Diabetes and hypertension frequently coexist and constitute the most notorious combination for the pathogenesis of DR. Large clinical trials have clearly demonstrated that tight control of glycaemia(More)
OBJECTIVE Diabetic retinopathy displays the features of a neurodegenerative disease. Oxidative stress is involved in the pathogenesis of diabetic retinopathy. This investigation sought to determine(More)
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