Marian E. Williams

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Atypical prosody, often reported in children with Autism Spectrum Disorders, is described by a range of qualitative terms that reflect the eccentricities and variability among persons in the spectrum. We investigate various wordand phonetic-level features from spontaneous speech that may quantify the cues reflecting prosody. Furthermore, we introduce the(More)
We describe the development and utilization of a new imaging technology for plant biology, optical coherence microscopy (OCM), which allows true in vivo visualization of plants and plant cells. This novel technology allows the direct, in situ (e.g. plants in soil), three-dimensional visualization of cells and events in shoot tissues without causing damage.(More)
Timely access to mental health services is critical to successful treatment of adults with severe and persistent mental illness, and timeliness is a key quality indicator in calls for improvement to the health care system. Waiting weeks for a psychiatric appointment results in increased psychiatric hospitalizations, decompensation, and risk for suicide.(More)
Increasingly, multimodal human-computer interactive tools are leveraged in both autism research and therapies. Embodied conversational agents (ECAs) are employed to facilitate the collection of socio-emotional interactive data from children with autism. In this paper we present an overview of the Rachel system developed at the University of Southern(More)
Review of 78 evaluations for 29 young children examined practices used in assessment of autism spectrum disorders in three settings: public schools, developmental disabilities eligibility determinations, and our hospital-based early childhood mental health program. While similar rates of classification of autism spectrum disorders were found across sites,(More)
We introduce the USC CARE Corpus, comprised of spontaneous and standardized child-psychologist interactions of children with a diagnosis of an autism spectrum disorder (ASD). The audio-video data is collected in the context of the Autism Diagnostic Observation Schedule (ADOS), which is a tool used by psychologists for a research-level diagnosis of ASD for(More)
Embodied conversational agents (ECA) offer platforms for the collection of structured interaction and communication data. This paper discusses the data collected from the Rachel system, an ECA developed at the University of Southern California, for interactions with children with autism. Two dyads each composed of a child with autism and his parent(More)
AIM This study examined the utility of standard autism diagnostic measures in nine children (aged 5-9y) with severe vision impairment and a range of social and language functioning. METHOD The Autism Diagnostic Observation Schedule (ADOS) and the Autism Diagnostic Interview, Revised (ADI-R) were systematically modified and used to assess symptoms of(More)
A motion-sensitive en-face-scanning 3-D optical coherence microscope (OCM) has been designed and constructed to study critical events in the early development of plants and animals. We describe the OCM instrument and present time-lapse movies of frog gastrulation, an early developmental event in which three distinct tissue layers are established that later(More)
PURPOSE The purpose of this study was to examine relationships between prosodic speech cues and autism spectrum disorder (ASD) severity, hypothesizing a mutually interactive relationship between the speech characteristics of the psychologist and the child. The authors objectively quantified acoustic-prosodic cues of the psychologist and of the child with(More)